Daniel H. Sterman, MD

  • Specialties: Pulmonary Medicine, Critical Care
  • Language: English
  • Phone: 212-731-6162
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About Me

I chose to specialize in interventional pulmonology because it offers the opportunity to perform hands-on procedures that directly help patients, and it involves innovative research into new treatments for lung disease. Interventional pulmonology began to emerge as a medical specialty as I was finishing medical school, so I had the chance to work with pioneers who built the specialty into what it is today—a hybrid of pulmonary medicine and thoracic surgery, in which we perform minimally invasive procedures to diagnose and treat people with cancers of the chest.

I evaluate patients at NYU Langone Pulmonary and Critical Care Associates and Perlmutter Cancer Center, diagnosing and treating people who have lung cancer, malignant pleura mesothelioma—a rare cancer affecting the membranes lining the lungs—and pleural effusion, which is a buildup of fluid between those membranes. I diagnose and manage cancers and benign disorders affecting the large airways of the lungs: the trachea and bronchi. I also perform staging procedures to determine the degree of advancement of a person’s condition.

When someone first comes to my office, we sit down and have an in-depth discussion about his or her medical history. I talk to family members and friends to obtain detailed background information about my patient’s experiences. When I have this information, I use a physical exam, imaging tests, and discussions with other NYU Langone specialists to create a specific diagnostic, staging, or treatment plan.

This holistic and patient-centered approach to care is the foundation of all care at Perlmutter Cancer Center and NYU Langone Pulmonary and Critical Care Associates. When patients come to see me at Perlmutter Cancer Center, they can also visit with chemotherapy and radiation experts—thoracic medical oncologists and thoracic radiation oncologists, respectively—as well as thoracic surgeons, all in the same afternoon. We aim to make the visit as positive as possible, the procedures as safe as possible, and the treatments as easy as possible for every patient. 

We are also building on a long and historic track record of advancements in pulmonary and critical care medicine here at NYU Langone. In addition to offering a variety of chest services across the hospital, we participate in novel research and clinical trials. I have spent the last 18 years studying ways to use gene therapy and immunotherapy to control tumors of the chest, treat people with both lung cancer and malignant pleural mesothelioma, and improve and prolong the quality of patients’ lives.

Conditions and Treatments

lung cancer, lung metastasis, pleural effusion, mesothelioma, tracheal stenosis, mediastinal disease, mediastinal tumor, solitary fibrous tumor, adenoid cystic carcinoma of the lung, lung mass, malignant mesothelioma, thoracic cancer, neuroendocrine tumor of the lung, mediastinal lymphadenopathy, lung carcinoma, neuroendocrine tumor of the lung, coughing up blood, thymus cancer, mucoepidermoid carcinoma of the lung, small cell lung cancer, non-small cell lung cancer
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  • Thomas and Suzanne Murphy Professor of Pulmonary and Critical Care Medicine, Department of Medicine
  • Professor, Department of Cardiothoracic Surgery
  • Director Multidiciplinary Pulmonary Oncology Prog
  • Dir Div Pulmry Critical Care Med & Sleep Medicine
Board Certifications
  • American Board of Internal Medicine (Pulmonary Disease), 1996
Education and Training
  • Fellowship, University of Pennsylania, Cardiovascular Research Group, Pulm & Critical Care, 1996
  • Fellowship, NA, 1996
  • Fellowship, NA, 1993
  • Residency, University of Pennsylania, Cardiovascular Research Group, Medicine, 1992
  • MD from Cornell University, 1989

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NYU Langone Laura and Isaac Perlmutter Cancer Center

160 East 34th Street, 8th Floor
New York, NY 10016

NYU Pulmonary & Critical Care Associates

530 1st Avenue, HCC, Suite 5D
New York, NY 10016

NYU Pulmonary & Critical Care Associates - 5B

530 1st Avenue, Suite 5B
NEW YORK, New York 10016

Research My Research


gene therapy, immunotherapy, tumor vaccines, thoracic malignancies

Research Summary

Dr. Sterman’s research interests are related to the treatment of thoracic malignancies, specifically as they apply to the synergy of molecular medicine and novel technologies in Interventional Pulmonology.  Over the past 17 years, he has focused on the translation of laboratory discoveries from the bench to the bedside: conducting Phase I human clinical trials of gene therapy and vaccine therapy for lung cancer, mesothelioma, and other pleural malignancies. Dr. Sterman is the lead clinical investigator in the multidisciplinary Thoracic Oncology Research Group at Penn and has been the Principal Investigator of Project 1 (Clinical Trials Project) for this NCI Program Project Grant since 1998. He is currently the sponsor and Principal Investigator of the ongoing Ad.IFN gene therapy trial aimed at patients with malignant pleural mesothelioma. Dr. Sterman and colleagues are developing trials involving delivery of the interferon-alpha gene via adenoviral vector in combination with standard chemotherapy, based upon success in pre-clinical studies, as well as with other immunomodulatory agents.  He is also a co-investigator on a clinical trial of intrapleural injection of a recombinant, replication-incompetent adenoviral viral vector expressing the HSV-TK gene with patients with malignant pleural effusions.  In addition, Dr. Sterman has also been involved in pioneering clinical research aimed at developing advanced bronchoscopic techniques to treat diseases such as severe asthma, emphysema and prolonged post-operative air leaks, as well as novel diagnostic and therapeutic approaches for peripheral lung cancers.  He is a prior president of the International Mesothelioma Interest Group and a former member of the scientific advisory board of the Mesothelioma Applied Research Foundation.


Research Interests Timeline

These focus areas and their associated publications are derived from PubMed and the MeSH term library.
represents one publication


  • Tsay, Jun-Chieh J; Wu, Benjamin G; Badri, Michelle H; Clemente, Jose C; Shen, Nan; Meyn, Peter; Li, Yonghua; Yie, Ting-An; Lhakhang, Tenzin; Olsen, Evan; Murthy, Vivek; Michaud, Gaetane; Sulaiman, Imran; Tsirigos, Aristotelis; Heguy, Adriana; Pass, Harvey; Weiden, Michael D; Rom, William N; Sterman, Daniel H; Bonneau, Richard; Blaser, Martin J; Segal, Leopoldo N

    American journal of respiratory & critical care medicine. 2018 Nov 01; 198(9):1188-1198

  • Feller-Kopman, David J; Reddy, Chakravarthy B; DeCamp, Malcolm M; Diekemper, Rebecca L; Gould, Michael K; Henry, Travis; Iyer, Narayan P; Lee, Y C Gary; Lewis, Sandra Z; Maskell, Nick A; Rahman, Najib M; Sterman, Daniel H; Wahidi, Momen M; Balekian, Alex A

    American journal of respiratory & critical care medicine. 2018 Oct 01; 198(7):839-849

  • Kindler, Hedy L; Rusch, Valerie; Bueno, Raphael; Ismaila, Nofisat; Pass, Harvey; Sterman, Daniel; Hassan, Raffit

    Journal of clinical oncology. 2018 Sep 10; 36(26):2746-2747

Read All Publications (120)

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