About Me
I was born in Brooklyn, and although I lived elsewhere during college and residency training, I consider myself a lifelong New Yorker. While getting my MD and PhD in molecular pharmacology from Albert Einstein College of Medicine in the Bronx, I realized I was especially fascinated by the field of dermatology. I loved taking care of children when I rotated through pediatrics as a medical student, so I chose to combine these interests and specialize in pediatric and adolescent dermatology.
I arrived at NYU Langone in 1990, joining one of the leading dermatology departments in the world. Whether treating a newborn or a college student, I want to do everything I can to help my patients and to support their families, while always balancing the benefits and risks of a particular treatment.
In my research, I have worked to determine the risks associated with certain birthmarks and skin growths, such as hemangiomas, and have collaborated with molecular geneticists to identify genetic changes that cause congenital skin conditions. I’ve also worked to improve how we treat eczema and psoriasis in children and teenagers. In 2003, I received a Lifetime Achievement Award from the American Skin Association.
Conditions and Treatments
Conditions
- acne
- atopic dermatitis
- birthmark
- eczema & dermatitis
- fungal infection
- genetic skin disease
- hair disease
- hair loss
- hemangioma
- lichen planus
- mole
- pigmentation disorder
- psoriasis
- seborrheic dermatitis
- skin disease
- squamous cell carcinoma
- vitiligo
Treatments
- annual skin check
- skin cancer screening
Learn more about conditions we treat at NYU Langone:
Acne , Birthmarks in Children , Eczema & Dermatitis , Psoriasis , VitiligoCredentials
Positions
- Professor, Department of Cell Biology at NYU Grossman School of Medicine
- Professor, Department of Pediatrics at NYU Grossman School of Medicine
- Samuel Weinberg Professor of Pediatric Dermatology, Ronald O. Perelman Department of Dermatology at NYU Grossman School of Medicine
- Chair, Ronald O. Perelman Department of Dermatology
- Director, Program in Cutaneous Biology
Board Certifications
- American Board of Dermatology (Pediatric Dermatology), 2004
- American Board of Dermatology - Dermatology, 1990
Education and Training
- Fellowship, Yale - New Haven Medical Center, Pediatric Dermatology, 1990
- Residency, Yale - New Haven Medical Center, Dermatology, 1989
- MD from Albert Einstein College of Med, 1986
- PhD from Albert Einstein College of Med, 1986
Is this your profile?
Edit profileInsurance Plans Accepted
This provider accepts the following insurance plans.
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Anthem Blue Cross Blue Shield
- BCBS EPO (LICH Employees)
- BCBS EPO - Empire EPO (NYU Langone Employees)
- BCBS EPO - Empire EPO (Sunset Park/Family Health Center Employees)
- BCBS EPO - Empire NYU Care (NYU Langone Employees)
- BCBS EPO - Empire NYU Care (Sunset Park/Family Health Center Employees)
- BCBS PPO - Empire PPO (Sunset Park/Family Health Center Employees)
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Sedgwick WTC
- World Trade Center - Sedgwick
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United Healthcare
- United Healthcare EPO (NYU Langone Health Employees)
- United Healthcare Indemnity (NYU Langone Health Employees)
- United Healthcare NYU Care (NYULH Employees)
- United Healthcare Plus (NYU Langone Health Employees)
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WTC Health Program
- NY Fire Department - WTC
- WTC Health Program
Seth J. Orlow, MD, PhD does not accept insurance.
Locations and Appointments
Video Visits
See a doctor from your mobile device instead of an in-person appointment. Learn more about video visits.
Schedule a Video VisitNYU Langone Dermatologic Associates
222 East 41st Street, 16th Floor, New York, NY 10017
“My research has improved treatments for eczema and psoriasis in children and teenagers.”
Seth J. Orlow, MD, PhD Pediatric Dermatologist
Research My Research
Interests
development of novel targeted therapies in melanoma and other cancers, molecular and cellular basis of pigmentation, cancer, pharmacology
Research Summary
1. Development of novel therapeutics for the treatment of a number of cancers including melanoma and multiple myeloma, as well as unraveling pathways underlying chemoresistance in these tumors. To do so, we utilize small molecule screening of already-approved drugs ("drug repositioning") and of natural products combined with molecular and cellular techniques. 2. Understanding the cell biology of melanin synthesis and deposition in the skin, hair and eyes, including the processing and trafficking of tyrosinase, the rate-limiting enzyme in melanin production, as well as the pathogenesis of various forms of oculocutaneous albinism that diminish pigmentation. 3. Elucidating the pathogenesis of vitiligo, in which melanocytes in the skin are destroyed, including the role of endoplasmic reticulum stress and the unfolded protein response.
Academic Contact
Academic office
222 East 41st Street
16th Floor
New York, NY 10017
Phone
Fax
Research Interests Timeline
Publications
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Jairath, Neil K.; Ramachandran, Vignesh; Orlow, Seth J.
Journal of Medical Artificial Intelligence. 2024 Sep 30; 7:?-?
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Strome, Arianna; Moshiri, Ata S; Orlow, Seth J
JAMA otolaryngology-- head & neck surgery. 2024 Jul 01; 150(7):621-622
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,; Moussa, Anthony; Bennett, Michaela; Wall, Dmitri; Meah, Nekma; York, Katherine; Bokhari, Laita; Asfour, Leila; Rees, Huw; Abraham, Leonardo Spagnol; Asz-Sigall, Daniel; Basmanav, Fitnat Buket; Bergfeld, Wilma; Betz, Regina C; Bhoyrul, Bevin; Blume-Peytavi, Ulrike; Callender, Valerie; Chitreddy, Vijaya; Combalia, Andrea; Cotsarelis, George; Craiglow, Brittany; Dhurat, Rachita; Donovan, Jeff; Doroshkevich, Andrei; Eisman, Samantha; Farrant, Paul; Ferrando, Juan; Gadzhigoroeva, Aida; Green, Jack; Grimalt, Ramon; Harries, Matthew; Hordinsky, Maria; Irvine, Alan; Jolliffe, Victoria; Kaiumov, Spartak; King, Brett; Lee, Joyce; Lee, Won-Soo; Li, Jane; Lortkipanidze, Nino; McMichael, Amy; Mesinkovska, Natasha Atanaskova; Messenger, Andrew; Mirmirani, Paradi; Olsen, Elise; Orlow, Seth J; Ovcharenko, Yuliya; Piraccini, Bianca Maria; Pirmez, Rodrigo; Rakowska, Adriana; Reygagne, Pascal; Rudnicka, Lidia; Corralo, David Saceda; Senna, Maryanne; Shapiro, Jerry; Sharma, Pooja; Siliuk, Tatiana; Starace, Michela; Suchonwanit, Poonkiat; Takwale, Anita; Tosti, Antonella; Vañó-Galván, Sergio; Visser, Willem I; Vogt, Annika; Wade, Martin; Yip, Leona; Zhou, Cheng; Sinclair, Rodney
JAMA dermatology. 2024 Mar 01; 160(3):341-350