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Paul E. Oberstein, MD

  • Specialty: Medical Oncology
  • Language: English
  • Phone: 212-731-6120
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Leading Researcher
Pancreatic Cancer Clinical Trials
Director
Gastrointestinal Medical Oncology Program
Recipient
Young Investigator Award, American Society of Clinical Oncology
Specialist
Pancreatic and Gastrointestinal Cancers

About Me

I was drawn to a career in medicine because of my dual interests in science and working with people. I wanted to use emerging scientific discoveries to change people’s lives and manage their illnesses, which led me to the specialty of gastrointestinal oncology. Because I had a strong research background in the field and a commitment to sharing new insights with patients, I knew it was an area that would allow me to make substantial contributions.

As a medical oncologist who focuses on cancers of the gastrointestinal tract, I treat people with various types of cancer, including stomach, pancreatic, colorectal, bile duct, and liver cancers. I am also the assistant director of the Pancreatic Cancer Center, part of NYU Langone’s Perlmutter Cancer Center, where we focus exclusively on research and treatment for people who have pancreatic cancer.

At Perlmutter Cancer Center, we take a patient-centered and collaborative approach to care. We understand that we’re caring for people who have conditions that can be difficult to manage, and are sensitive to the full spectrum of their needs. We want to address all of the issues a patient is confronting, including treating and alleviating cancer-related symptoms. The care we provide is unique because we can involve many specialists across our network at the same time. This allows us to address all aspects of a person’s care and begin treatment as quickly as possible.

We have a deep commitment to education, and our aim is to effectively communicate disease and treatment information to our patients. We often have the opportunity to offer new treatments, and we want patients to understand these options and actively participate in their own care. There are many moving parts in cancer care, and we make sure to present the data as clearly as possible so our patients understand every facet of the process. All of our experts share this philosophy.

Our treatments are research-driven. We participate in many clinical trials with the hope of providing our patients with newer and better treatment options, such as immunotherapy and novel chemotherapy combinations, along with better supportive and nutritional care. We also focus on translational research, which means we collaborate with scientists who have made novel discoveries and help translate these discoveries into new treatments. Our goal is to involve our patients in our research so we can develop new insights on difficult-to-treat cancers and apply these discoveries to patient care in a fast and practical way.

I am a member of the American Society of Clinical Oncology (ASCO) and the American Association for Cancer Research. I am also the recipient of an ASCO Young Investigator Award for my work in clinical trials and a KL2 Career Development Award from the National Cancer Institute. I currently run and participate in numerous clinical trials, and encourage every person I treat to learn more about clinical trials and play an active role in his or her treatment.


Conditions and Treatments

stomach cancer, colorectal cancer screening, anal cancer, esophageal cancer, hereditary nonpolyposis colorectal cancer, pancreatic cancer, colorectal cancer, biliary cancer, gastrointestinal neuroendocrine tumor, liver cancer, gastrointestinal cancer, colorectal surgery
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Credentials

Positions
  • Assistant Professor, Department of Medicine
  • Assistant Director, Pancreatic Cancer Center
  • Dir, Gastrointestinal Medical Oncology Program
Board Certifications
  • American Board of Internal Medicine (Medical Oncology), 2014
  • American Board of Internal Medicine - Internal Medicine, 2009
Education and Training
  • Fellowship, Columbia Presbyterian Med Ctr (New York, NY), Hematology Oncology, 2013
  • Residency, Temple University Hospital, Internal Medicine, 2009
  • MD from Ohio State University, 2006
Departments

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NYU Medical Oncology Associates

160 East 34th Street, 9th Floor
New York, NY 10016

Clinical Trials and Research Studies

  • A Phase III Multicenter Open-Label Randomized Trial to Evaluate Efficacy and Safety of FOLFIRINOX (FFX) versus Combination of CPI-613 with modified FOLFIRINOX (mFFX) in Patients with Metastatic Adenocarcinoma of the Pancreas

    Learn More
  • A Randomized Phase 2 Study of Losartan and Nivolumab in Combination with FOLFIRINOX and SBRT in Localized Pancreatic Cancer (Stand up to Cancer)

    Learn More
  • A Phase l/ll Open-Label Study to Investigate the Safety Clinical Activity Pharmacokinetics and Pharmacodynamics of GSK3145095 Administered Alone and in Combination with Anticancer Agents Including Pembrolizumab in Adult Participants with Selected Advanced Solid Tumors

    Learn More
View All Research Studies (15)

Publications

  • Maurer, Hans Carlo; Holmstrom, Sam R; He, Jing; Laise, Pasquale; Su, Tao; Ahmed, Aqeel; Hibshoosh, Hanina; Chabot, John A; Oberstein, Paul E; Sepulveda, Antonia R; Genkinger, Jeanine M; Zhang, Jiapeng; Iuga, Alina C; Bansal, Mukesh; Califano, Andrea; Olive, Kenneth P

    Gut : journal of the British Society of Gastroenterology. 2019 Jan 18;

  • Cholinergic Signaling via Muscarinic Receptors Directly and Indirectly Suppresses Pancreatic Tumorigenesis and Cancer Stemness [Meeting Abstract]

    Renz, B. W.; Tanaka, T.; Sunagawa, M.; Takahasi, R.; Macchini, M.; Dantes, Z.; Valenti, G.; Ilmer, M.; Westphalen, C. B.; Reichert, M.; Oberstein, P. E.; Iuga, A. C.; Werner, J.; Olive, K. P.; Wang, T. C.

    Pancreas. 2018 NOV-DEC; 47:1418-1419

  • Renz, Bernhard W; Tanaka, Takayuki; Sunagawa, Masaki; Takahashi, Ryota; Jiang, Zhengyu; Macchini, Marina; Dantes, Zahra; Valenti, Giovanni; White, Ruth A; Middelhoff, Moritz A; Ilmer, Matthias; Oberstein, Paul E; Angele, Martin K; Deng, Huan; Hayakawa, Yoku; Westphalen, C Benedikt; Werner, Jens; Remotti, Helen; Reichert, Maximilian; Tailor, Yagnesh H; Nagar, Karan; Friedman, Richard A; Iuga, Alina C; Olive, Kenneth P; Wang, Timothy Cragin

    Cancer discovery. 2018 Nov ; 8(11):1458-1473

Read All Publications (35)

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