Cardiac Amyloidosis Care

Our specialists at the Amyloidosis Program provide expert care for cardiac amyloidosis, a serious condition that affects heart function.

Cardiac amyloidosis occurs when a protein, called amyloid fibrils, accumulates in the heart muscle and surrounding tissues. This protein buildup causes the walls of the heart to thicken, making it harder for the heart to pump blood. Amyloid fibrils can also build up in the nervous system and other organs, such as the kidneys.

Symptoms—including shortness of breath, swelling in the legs, or cardiac arrhythmias, such as atrial fibrillation—are often mistaken for those of hypertensive heart disease, hypertrophic cardiomyopathy, or other forms of heart failure.

As part of NYU Langone’s Perlmutter Cancer Center, our team of cardiologists, neurologists, hematologists, and nephrologists works together to create a comprehensive treatment plan that addresses all aspects of this condition.

Diagnosis and Treatment for Cardiac Amyloidosis

Proper treatment requires an accurate diagnosis. At NYU Langone, we have the advanced imaging technology, laboratory testing resources, and expertise to identify cardiac amyloidosis. For most people, we first conduct a blood test to determine the type of amyloid present in the body. Other tests, including a biopsy, may be performed as well.

Depending on the type of amyloidosis, we may prescribe medications that can slow or prevent the abnormal proteins from being formed. Specialists at NYU Langone’s Heart Failure Advanced Care Center and Heart Rhythm Center can also help manage symptoms of cardiac amyloidosis.

When appropriate, we refer patients for a heart transplant through the NYU Langone Transplant Institute. We can also enroll you in clinical trials, to provide you with the latest treatment options.