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William L. Carroll, MD

  • Specialty: Pediatric Hematology—Oncology
  • Language: English
  • Phone: 212-263-9906
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About Me

At NYU Langone’s Stephen D. Hassenfeld Children’s Center for Cancer and Blood Disorders, I treat children who have pediatric malignancies, such as leukemia and lymphoma. My personal philosophy and our team’s goal is to provide individualized treatment that fits each child.

We don’t just treat patients—we care for children and their families. We use a 360-degree approach that extends beyond medical treatment, aiming to improve diet and nutrition and reduce the psychological, social, and spiritual burden of illness. The cure rate for childhood cancers has improved dramatically, but we want children and their families to continue to live their lives as healthfully as possible, so we focus on the future from the first day of treatment.

As an oncologist involved in several national committees, I have an appreciation of where oncology is headed and how it has changed. I perform research that is funded by the National Cancer Institute and focused on discovering the molecular origins of childhood cancers. I use this research to develop better treatments and, someday, preventive measures. We are also developing precision medicine, in which we use the genetic makeup of a tumor to understand its vulnerabilities.


Conditions and Treatments

Conditions
  • leukemia
  • lymphoma
  • blood disorder
  • anemia
  • platelet disorder
  • pancytopenia
  • Wilms tumor
  • bone sarcoma
  • neuroblastoma
  • bone cancer
  • bone tumor
  • kidney cancer
  • soft tissue sarcoma
  • blood cancer
  • renal cell carcinoma
  • Hodgkin lymphoma
  • AIDS-related lymphoma
  • male germ cell tumor
Treatments
  • stem cell transplant

Credentials

Positions
  • Julie and Edward J. Minskoff Professor of Pediatrics, Department of Pediatrics
  • Professor, Department of Pathology
  • Associate Chair for Clinical and Translational Research, Department of Pediatrics
Board Certifications
  • American Board of Pediatrics (Pediatric Hematology-Oncology), 1987
  • American Board of Pediatrics - Pediatrics, 1984
Education and Training
  • Fellowship, Stanford University Hospital, Hematology Oncology, 1987
  • Fellowship, Stanford University Hospital, Peds Hem/Oncology, 1984
  • Residency, Children's Hospital Medical Center, Pediatrics, 1982
  • MD from University Of California, 1978
Departments

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Insurance Plans Accepted

This provider accepts the following insurance plans.

  • Aetna
    • Aetna HMO
    • Aetna Indemnity
    • Aetna International
    • Aetna Medicare Managed Care
    • Aetna Meritain Health
    • Aetna Open Access EPO
    • Aetna Open Access HMO
    • Aetna POS
    • Aetna POS (American Express Employer)
    • Aetna PPO
    • Aetna Signature Administrators PPO
    • Aetna Student Plan
    • Allied
    • Chesterfield Resources Inc
    • Christian Brothers Services
    • CoreSource
    • Healthscope
    • Nippon Life of America-Aetna
    • Nippon Life-Aetna
    • Starmark
    • WellNet
  • Amida Care
    • Amida Care Medicaid
  • Blue Cross Blue Shield
    • BCBS Blue Access EPO Large Group
    • BCBS Blue Access EPO Small Group
    • BCBS Blue Access GEPO Large Group
    • BCBS Blue Access GEPO Small Group
    • BCBS Blue Access HMO Small Group
    • BCBS Blue Access PPO Large Group
    • BCBS EPO
    • BCBS EPO (BlackRock Employees)
    • BCBS EPO (NYU Winthrop Employees)
    • BCBS EPO - Empire EPO (NYU Langone Employees)
    • BCBS EPO - Empire EPO (Sunset Park/Family Health Center Employees)
    • BCBS EPO - Empire NYU Care (NYU Langone Employees)
    • BCBS EPO - Empire NYU Care (NYU Winthrop Employees)
    • BCBS EPO - Empire NYU Care (Sunset Park/Family Health Center Employees)
    • BCBS Federal Program
    • BCBS HMO
    • BCBS Indemnity
    • BCBS Local 32BJ Employees
    • BCBS Mediblue Medicare HMO
    • BCBS Mediblue Medicare PPO
    • BCBS Open Access HMO
    • BCBS POS
    • BCBS PPO
    • BCBS PPO (BlackRock Employees)
    • BCBS PPO (NYU Winthrop Employees)
    • BCBS PPO - Empire PPO (Sunset Park/Family Health Center Employees)
    • BCBS PPO/EPO Small Group
    • New York Hotel Trades
    • Unicare
  • Cigna
    • Apwu Health Plan
    • Cigna Great West PPO
    • Cigna HMO
    • Cigna Indemnity
    • Cigna Managed Care/POS
    • Cigna NALC
    • Cigna Open Access
    • Cigna Open Access PPO
    • Cigna PPO
    • Cigna Premier Plus
    • Consolidated Health Plans-NYU Student
    • Great West HMO
    • MVP-Cigna Network
  • Connecticare
    • Connecticare Commercial
  • Elderplan
    • Elderplan
    • Elderplan FIDA
  • Emblem
    • Emblem Select Care Basic Exchange
    • Emblem Select Care Bronze Exchange
    • Emblem Select Care Gold Exchange
    • Emblem Select Care Platinum Exchange
    • Emblem Select Care Silver Exchange
  • Empire BCBS Health Plus
    • BCBS Healthplus Essential Plan 1
    • BCBS Healthplus Essential Plan 2
    • BCBS Healthplus Essential Plan 3
    • BCBS Healthplus Essential Plan 4
    • BCBS Healthplus Gatekeeper exchange
    • BCBS Healthplus NY Child Health Plus NY
    • BCBS Healthplus NY Medicaid Managed Care NY
    • BCBS Healthplus Special Needs
  • Fidelis Care
    • Fidelis Care Bronze Exchange
    • Fidelis Care Catastrophic Cvg Exchange
    • Fidelis Care Child Health Plus
    • Fidelis Care Gold Exchange
    • Fidelis Care Medicaid Managed Care
    • Fidelis Care Medicare
    • Fidelis Care Native American Exchange
    • Fidelis Care Platinum Exchange
    • Fidelis Care Silver Exchange
    • Fidelis Essential Plan 1
    • Fidelis Essential Plan 2
    • Fidelis Essential Plan 3
    • Fidelis Essential Plan 4
  • GHI
    • American Plan Administrators
    • GHI CBP (City of New York Employees)
    • GHI Emblem Health EPO
    • GHI Emblem Health PPO
    • GHI HMO
    • GHI HMO Medicare
    • GHI Medicare PPO
    • GHI Medicare Supplement
    • GHI Network Access - Benefit Services of PA
    • GHI Network Access - Total Plan Concepts
    • IUOE Local 14-14B
    • Wlny-TV Inc.
  • HIP
    • Emblem Essential Plan 1
    • Emblem Essential Plan 2
    • Emblem Essential Plan 3
    • Emblem Essential Plan 4
    • HIP Access I
    • HIP Access II
    • HIP Bridge
    • HIP Child Health Plus
    • HIP EPO
    • HIP HMO
    • HIP Medicaid Enhanced Care
    • HIP Medicare VIP
    • HIP POS
    • HIP Prime Bronze
    • HIP Prime Gold
    • HIP Prime Platinum
    • HIP Prime Silver
    • HIP VIP Medicare - VIP Go
    • HIP Vytra Healthcare Managed Care
  • Health Smart
    • WTC Health Program-HHC
  • Healthfirst
    • Health And Recovery Plan (Harp)
    • Healthfirst Bronze Leaf Exchange
    • Healthfirst Bronze Total, Pro, Plus EPO
    • Healthfirst Child Health Plus
    • Healthfirst Essential Plan 1 & 2
    • Healthfirst Essential Plan 3 & 4
    • Healthfirst Gold Leaf Exchange
    • Healthfirst Gold Total, Pro, Plus EPO
    • Healthfirst Green Leaf Exchange
    • Healthfirst Medicaid
    • Healthfirst Medicare
    • Healthfirst Medicare/NYU Risk
    • Healthfirst Personal Wellness Plan
    • Healthfirst Platinum Leaf Exchange
    • Healthfirst Platinum Total, Pro, Plus EPO
    • Healthfirst Senior Health Partners
    • Healthfirst Silver Leaf Exchange
    • Healthfirst Silver Total, Pro, Plus EPO
  • Humana
    • Humana Medicare Advantage
  • Local 1199
    • Local 1199 - NYU Hospital Member Choice
    • Local 1199 PPO
  • Magnacare
    • Magnacare PPO
  • Medicaid of New Jersey - Molina
    • Medicaid NJ/Molina
  • Medicaid of New York
    • NYS Medicaid
  • Medicare
    • Medicare Part B
  • Metroplus
    • Metroplus Bronze Plus Plan Exchange
    • Metroplus Child Health Plus
    • Metroplus Essential Plan 1
    • Metroplus Essential Plan 2
    • Metroplus Essential Plan 3
    • Metroplus Essential Plan 4
    • Metroplus Gold
    • Metroplus Gold Care 2
    • Metroplus Gold Plus Plan Exchange
    • Metroplus Medicaid Managed Care
    • Metroplus Medicare
    • Metroplus Medplus Plan Exchange
    • Metroplus Platinum Plus Plan Exchange
    • Metroplus Silver Plus Plan Exchange
  • Multiplan
    • AXA Assistance USA
    • Administrative Concepts
    • Beech Street PPO
    • Diversified Administration Corporation
    • Fiserv Health
    • GEHA
    • Global Excel
    • Global Health
    • Guardian Life Insurance Co Of America
    • Health Net Of California
    • Health Republic Of NJ
    • Humana Health Plan
    • Insurance Design Administrators
    • Kaiser Foundation
    • Kaiser Permanente
    • Meritain Health
    • Multiplan PPO
    • Multiplan-Capital Dist Phys Health
    • Mutual Of Omaha
    • Nippon Life Ins Co
    • PHCS
    • Professional Benefit Admin
    • Qualcare Inc
    • Screen Actors Guild
    • Teamsters Allied Benefits
    • US Life Insurance Company
  • NYSHIP - The Empire Plan
    • NYS Health Insurance Plan - The Empire Plan
  • Oxford
    • Oxford Health Plans Freedom
    • Oxford Health Plans Liberty
  • POMCO Insurance Company
    • POMCO Insurance Company
  • Qualcare Inc.
    • Qualcare Direct
  • Railroad Medicare
    • Palmetto GBA Railroad Medicare
  • Tricare
    • TRICARE
    • TriWest
    • US Family Health Plan
  • United Healthcare
    • AARP Medicare Complete
    • Oxford Health Plans Medicare Advantage
    • UMR
    • UMR WTC Health Program
    • United Healthcare AARP
    • United Healthcare Choice
    • United Healthcare Choice (AMEX employees)
    • United Healthcare Choice (Blackrock employees)
    • United Healthcare Choice (CBS employees)
    • United Healthcare Choice NSLIJ
    • United Healthcare EPO
    • United Healthcare EPO (NYU Langone Health Employees)
    • United Healthcare HMO
    • United Healthcare Indemnity
    • United Healthcare Indemnity (NYU Langone Health Employees)
    • United Healthcare Medicare
    • United Healthcare Navigate
    • United Healthcare POS
    • United Healthcare PPO
    • United Healthcare Plus (NYU Langone Health Employees)
    • United Healthcare Student Resources
    • UnitedHealthcare Choice (JP Morgan Employees)
  • VNS Choice Advantage
    • VNS Medicaid Advantage
    • VNS Medicare Advantage
    • VNS NY Choice Select Health
  • Veterans Choice
    • Veterans Choice Program-VACAA
View All Accepted Plans This list of insurances changes regularly, and insurance plans listed may not be accepted at all office locations for this provider. Before your appointment, please confirm with your insurance company that this provider accepts your insurance.

Locations and Appointments

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Stephen D. Hassenfeld Childrens Center for Cancer & Blood Disorders

160 East 32nd Street, 3rd Floor
New York, NY 10016

Research My Research

Interests

cancer, pharmacology, childhood cancers, acute leukemia, apoptotic pathways in cancer cells, genomic and epigenomic analysis of childhood cancer, relapsed/resistant leukemia

Research Summary

In our laboratory we focus on two major challenges facing children with acute lymphoblastic leukemia (ALL). First, in spite of dramatic improvements in outcome, one in five children will suffer a relapse and then have a poor prognosis. Second, the physical and emotional costs of therapy for those who are cured are high, with short- and long-term side effects.

Therefore, we seek to understand mechanisms of drug resistance and to identify pathways unique to the cancer cell that can serve as targets for more effective, less toxic therapeutic approaches.

We use modern genomic and epigenomic methods to understand the genesis and evolution of ALL that leads to treatment failure. We have shown that resistant cancer cells acquire novel mutations that are responsible for drug resistance. In some cases, a small clone emerges through the selective effect of chemotherapy in a model reminiscent of Darwinian evolution. However, in other cases, such mutations may have been acquired during the course of treatment. Through years of effort we have created a “genetic fingerprint” of resistant cells and have used this information to pilot novel methods to prevent and treat relapse.

Most recently we have focused on the epigenome—molecular mechanisms that control gene activity that are not related to the DNA sequence itself. We have shown that DNA modifications, including methylation and histone changes, also allow the cancer cell to overcome therapy. The availability of new agents that target these epigenetic changes may allow for more effective treatment of relapsed disease and we are exploring this approach in laboratory models.

Our laboratory encompasses the full spectrum of investigation involving basic bench research, highly translational efforts using samples from patients, and clinical trials in children with ALL.

 

Research Interests Timeline

These focus areas and their associated publications are derived from PubMed and the MeSH term library. *
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Publications

Read All Publications (174)

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