Intraocular Melanoma in Adults

Our eye cancer specialists are leaders in diagnosing and treating intraocular melanoma, which begins in structures within the blood vessel-rich area of the eye known as the uvea. Our internationally recognized ophthalmic oncologists have pioneered many of the vision-sparing diagnostic and treatment approaches currently used for people with intraocular melanoma. Treatment is aimed at destroying the tumor, preserving vision, and preventing the disease from spreading.

Clinical Trials and Research Studies

Phase 1

Phase 1 Open-Label Multicenter Dose Escalation Study of mRNA-2752 a Lipid Nanoparticle Encapsulating mRNAs Encoding Human OX40L IL-23 and IL-36? for Intratumoral Injection Alone and in Combination with Immune Checkpoint Blockade

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Phase 3

A Phase 3 Randomized Double-blind Study of Adjuvant Immunotherapy with Relatlimab and Nivolumab Fixed-dose Combination versus Nivolumab Monotherapy after Complete Resection of Stage III-IV Melanoma

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Phase 2

The BAMM2 (BRAF Autophagy MEK inhibition in Melanoma) Study: A Randomized Double Blind Phase II Study of Dabrafenib and Trametinib with or without Hydroxychloroquine in Advanced BRAFV600E/K Melanoma with elevated LDH

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Phase 2

A Phase II Study of Biomarker Driven Early Discontinuation of Anti-PD-1 Therapy in Patients with Advanced Melanoma (PET-Stop) [EA6192]

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