Intraocular Melanoma in Adults

Our eye cancer specialists are leaders in diagnosing and treating intraocular melanoma, which begins in structures within the blood vessel-rich area of the eye known as the uvea. Our internationally recognized ophthalmic oncologists have pioneered many of the vision-sparing diagnostic and treatment approaches currently used for people with intraocular melanoma. Treatment is aimed at destroying the tumor, preserving vision, and preventing the disease from spreading.

Clinical Trials and Research Studies

Phase 2

MONETTE: A Randomised Open-Label Phase 2 Study of Ceralasertib Monotherapy and Ceralasertib plus Durvalumab in Patients with Unresectable or Advanced Melanoma and Primary or Secondary Resistance to PD-(L)1 Inhibition

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Phase 1

A Phase 1/1b Open-label Multicenter Study to Investigate the Safety Tolerability Pharmacokinetics and Antitumor Activity of KIN-2787 in Participants with BRAF and/or NRAS Mutation-positive Solid Tumors.

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Phase 3

Melanoma Margins Trial (MelMarT): A Phase III Multi-Centre Multi-National Randomised Control Trial Investigating 1cm v 2cm Wide Excision Margins for Primary Cutaneous Melanoma.

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Phase 5

Phase 1/2 Open-Label Rolling-Arm Umbrella Platform Design of Investigational Agents With or Without Pembrolizumab or Pembrolizumab Alone in Participants with Melanoma (KEYNOTE-U02): Substudy 02C

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