Intraocular Melanoma in Adults

Our eye cancer specialists are leaders in diagnosing and treating intraocular melanoma, which begins in structures within the blood vessel-rich area of the eye known as the uvea. Our internationally recognized ophthalmic oncologists have pioneered many of the vision-sparing diagnostic and treatment approaches currently used for people with intraocular melanoma. Treatment is aimed at destroying the tumor, preserving vision, and preventing the disease from spreading.

Clinical Trials and Research Studies

Phase 3

A Phase 3 Randomized Open-label Study to Compare Adjuvant Immunotherapy of Bempegaldesleukin Combined with Nivolumab Versus Nivolumab After Complete Resection of Melanoma in Patients at High Risk for Recurrence (PIVOT-12)

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Phase 5

A Phase 1/2 Open-Label Rolling-Arm Umbrella Platform Design of lnvestigational Agents With or Without Pembrolizumab or Pembrolizumab Alone in Participants with Melanoma (KEYNOTE-U02): Substudy 02B Ph 1/2 Substudy of 1L Oncological Treatment(s) in Advanced MEL

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Phase 5

A Phase 1/2 Open-Label Rolling-Arm Umbrella Platform Design of Investigational Agents With or Without Pembrolizumab or Pembrolizumab Alone in Participants with Melanoma (KEYNOTE-U02): Substudy 02A

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Phase 2

A randomized open-label multi-arm two-part phase II study to assess efficacy and safety of multiple LXH254 combinations in patients with previously treated unresectable or metastatic BRAFV600 or NRAS mutant melanoma

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