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NYU Langone Provider

Douglas S. Holmes, MD

NYU Langone Provider
  • Specialties: Cardiac Electrophysiology, Cardiology
  • Language: English
  • Phone: 212-263-7149
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Conditions and Treatments

  • cardiac device implant
  • sarcoidosis
  • fainting
  • slow heartbeat
  • complication associated with cardiac implant
  • atrial fibrillation
  • congenital heart disease
  • heart throbbing
  • ventricular arrhythmia
  • dilated cardiomyopathy
  • atrial flutter
  • abnormal heart rhythms
  • long QT syndrome
  • ventricular fibrillation
  • congenital heart defect
  • Brugada syndrome
  • rapid heartbeat
  • ventricular tachycardia
  • pacemaker placement
  • automatic implantable cardioverter-defibrillators
  • cardiac lead extraction
  • electrophysiology

Board Certifications
  • American Board of Internal Medicine (Clinical Cardiac Electrophysiology), 1999
  • American Board of Internal Medicine (Cardiovascular Disease), 1998
Education and Training
  • Fellowship, NYU Medical Center, Cardiac Electrophysiology, 1999
  • Fellowship, NYU Medical Center, Cardiology, 1998
  • Residency, NYU Medical Center, 1995
  • MD from Columbia University, 1987

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This provider accepts the following insurance plans.

  • Aetna
    • Aetna HMO
    • Aetna Indemnity
    • Aetna International
    • Aetna Medicare Managed Care
    • Aetna Meritain Health
    • Aetna Open Access EPO
    • Aetna Open Access HMO
    • Aetna POS
    • Aetna POS (American Express Employer)
    • Aetna PPO
    • Aetna Signature Administrators PPO
    • Aetna Student Plan
    • Allied
    • Chesterfield Resources Inc
    • Christian Brothers Services
    • CoreSource
    • Healthscope
    • Nippon Life of America-Aetna
    • Nippon Life-Aetna
    • Starmark
    • WellNet
  • Agewell
    • Agewell Managed Medicaid
    • Agewell Medicare
  • Amida Care
    • Amida Care Medicaid
  • Blue Cross Blue Shield
    • BCBS Blue Access EPO Large Group
    • BCBS Blue Access EPO Small Group
    • BCBS Blue Access GEPO Large Group
    • BCBS Blue Access GEPO Small Group
    • BCBS Blue Access HMO Small Group
    • BCBS Blue Access PPO Large Group
    • BCBS EPO
    • BCBS EPO (BlackRock Employees)
    • BCBS EPO (NYU Winthrop Employees)
    • BCBS EPO - Empire EPO (NYU Langone Employees)
    • BCBS EPO - Empire EPO (Sunset Park/Family Health Center Employees)
    • BCBS EPO - Empire NYU Care (NYU Langone Employees)
    • BCBS EPO - Empire NYU Care (NYU Winthrop Employees)
    • BCBS EPO - Empire NYU Care (Sunset Park/Family Health Center Employees)
    • BCBS Federal Program
    • BCBS HMO
    • BCBS Indemnity
    • BCBS Local 32BJ Employees
    • BCBS Mediblue Medicare HMO
    • BCBS Mediblue Medicare PPO
    • BCBS POS
    • BCBS PPO
    • BCBS PPO (BlackRock Employees)
    • BCBS PPO (NYU Winthrop Employees)
    • BCBS PPO - Empire PPO (Sunset Park/Family Health Center Employees)
    • BCBS PPO/EPO Small Group
    • New York Hotel Trades
  • Cigna
    • Apwu Health Plan
    • Cigna Great West PPO
    • Cigna HMO
    • Cigna Indemnity
    • Cigna Managed Care/POS
    • Cigna NALC
    • Cigna Open Access
    • Cigna Open Access PPO
    • Cigna PPO
    • Cigna Premier Plus
    • Consolidated Health Plans-NYU Student
    • Great West HMO
    • MVP-Cigna Network
  • Connecticare
    • Connecticare Commercial
  • Elderplan
    • Elderplan
    • Elderplan FIDA
  • Emblem
    • Emblem Select Care Basic Exchange
    • Emblem Select Care Bronze Exchange
    • Emblem Select Care Gold Exchange
    • Emblem Select Care Platinum Exchange
    • Emblem Select Care Silver Exchange
  • Empire BCBS Health Plus
    • BCBS Healthplus Essential Plan 1
    • BCBS Healthplus Essential Plan 2
    • BCBS Healthplus Essential Plan 3
    • BCBS Healthplus Essential Plan 4
    • BCBS Healthplus Gatekeeper exchange
    • BCBS Healthplus NY Child Health Plus NY
    • BCBS Healthplus NY Medicaid Managed Care NY
    • BCBS Healthplus Special Needs
  • Fidelis Care
    • Fidelis Care Bronze Exchange
    • Fidelis Care Catastrophic Cvg Exchange
    • Fidelis Care Child Health Plus
    • Fidelis Care Gold Exchange
    • Fidelis Care Medicaid Managed Care
    • Fidelis Care Medicare
    • Fidelis Care Native American Exchange
    • Fidelis Care Platinum Exchange
    • Fidelis Care Silver Exchange
    • Fidelis Essential Plan 1
    • Fidelis Essential Plan 2
    • Fidelis Essential Plan 3
    • Fidelis Essential Plan 4
  • GHI
    • American Plan Administrators
    • GHI CBP (City of New York Employees)
    • GHI Emblem Health EPO
    • GHI Emblem Health PPO
    • GHI HMO
    • GHI HMO Medicare
    • GHI Medicare PPO
    • GHI Medicare Supplement
    • GHI Network Access - Benefit Services of PA
    • GHI Network Access - Total Plan Concepts
    • IUOE Local 14-14B
    • Wlny-TV Inc.
  • HIP
    • Emblem Essential Plan 1
    • Emblem Essential Plan 2
    • Emblem Essential Plan 3
    • Emblem Essential Plan 4
    • HIP Access I
    • HIP Access II
    • HIP Bridge
    • HIP Child Health Plus
    • HIP EPO
    • HIP HMO
    • HIP Medicaid Enhanced Care
    • HIP Medicare VIP
    • HIP POS
    • HIP Prime Bronze
    • HIP Prime Gold
    • HIP Prime Platinum
    • HIP Prime Silver
    • HIP VIP Medicare - VIP Go
    • HIP Vytra Healthcare Managed Care
  • Health Smart
    • WTC Health Program-HHC
  • Healthfirst
    • Health And Recovery Plan (Harp)
    • Healthfirst Bronze Leaf Exchange
    • Healthfirst Bronze Total, Pro, Plus EPO
    • Healthfirst Child Health Plus
    • Healthfirst Essential Plan 1 & 2
    • Healthfirst Essential Plan 3 & 4
    • Healthfirst Gold Leaf Exchange
    • Healthfirst Gold Total, Pro, Plus EPO
    • Healthfirst Green Leaf Exchange
    • Healthfirst Medicaid
    • Healthfirst Medicare
    • Healthfirst Medicare/NYU Risk
    • Healthfirst Personal Wellness Plan
    • Healthfirst Platinum Leaf Exchange
    • Healthfirst Platinum Total, Pro, Plus EPO
    • Healthfirst Senior Health Partners
    • Healthfirst Silver Leaf Exchange
    • Healthfirst Silver Total, Pro, Plus EPO
  • Humana
    • Humana Medicare Advantage
  • Local 1199
    • Local 1199 - NYU Hospital Member Choice
    • Local 1199 PPO
  • Magnacare
    • Magnacare PPO
  • Medicaid of New York
    • NYS Medicaid
  • Medicare
    • Medicare Part B
  • Metroplus
    • Metroplus Bronze Plus Plan Exchange
    • Metroplus Child Health Plus
    • Metroplus Essential Plan 1
    • Metroplus Essential Plan 2
    • Metroplus Essential Plan 3
    • Metroplus Essential Plan 4
    • Metroplus Gold
    • Metroplus Gold Care 2
    • Metroplus Gold Plus Plan Exchange
    • Metroplus Medicaid Managed Care
    • Metroplus Medicare
    • Metroplus Medplus Plan Exchange
    • Metroplus Platinum Plus Plan Exchange
    • Metroplus Silver Plus Plan Exchange
  • Multiplan
    • AXA Assistance USA
    • Administrative Concepts
    • Beech Street PPO
    • Diversified Administration Corporation
    • Fiserv Health
    • GEHA
    • Global Excel
    • Global Health
    • Guardian Life Insurance Co Of America
    • Health Net Of California
    • Health Republic Of NJ
    • Humana Health Plan
    • Insurance Design Administrators
    • Kaiser Foundation
    • Kaiser Permanente
    • Meritain Health
    • Multiplan PPO
    • Multiplan-Capital Dist Phys Health
    • Mutual Of Omaha
    • Nippon Life Ins Co
    • PHCS
    • Professional Benefit Admin
    • Qualcare Inc
    • Screen Actors Guild
    • Teamsters Allied Benefits
    • US Life Insurance Company
  • NYSHIP - The Empire Plan
    • NYS Health Insurance Plan - The Empire Plan
  • Oxford
    • Oxford Health Plans Freedom
    • Oxford Health Plans Liberty
  • POMCO Insurance Company
    • POMCO Insurance Company
  • Partners Health Plan Inc
    • Partners Health Plan FIDA
    • Partners Health Plan Medicaid
    • Partners Health Plan Medicare
  • Qualcare Inc.
    • Qualcare Direct
  • Railroad Medicare
    • Palmetto GBA Railroad Medicare
  • Tricare
    • TriWest
    • US Family Health Plan
  • United Healthcare
    • AARP Medicare Complete
    • AARP Medicare Complete Mosaic
    • Oxford Health Plans Medicare Advantage
    • UMR
    • UMR WTC Health Program
    • United Healthcare AARP
    • United Healthcare Choice
    • United Healthcare Choice (AMEX employees)
    • United Healthcare Choice (Blackrock employees)
    • United Healthcare Choice (CBS employees)
    • United Healthcare Choice (Viacom Employees)
    • United Healthcare Choice NSLIJ
    • United Healthcare EPO
    • United Healthcare EPO (NYU Langone Health Employees)
    • United Healthcare HMO
    • United Healthcare Indemnity
    • United Healthcare Indemnity (NYU Langone Health Employees)
    • United Healthcare Medicare
    • United Healthcare Navigate
    • United Healthcare POS
    • United Healthcare PPO
    • United Healthcare Plus (NYU Langone Health Employees)
    • United Healthcare Student Resources
    • United Healthcare Value, Advantage and HDHP (New York University employees)
    • UnitedHealthcare Choice (JP Morgan Employees)
  • VA Community Care Network
    • VA CCN Optum
  • VNS Choice Advantage
    • VNS Medicaid Advantage
    • VNS Medicare Advantage
    • VNS NY Choice Select Health
  • Veterans Choice
    • Veterans Choice Program-VACAA
  • Village Care
    • VillageCare
View All Accepted Plans This list of insurances changes regularly, and insurance plans listed may not be accepted at all office locations for this provider. Before your appointment, please confirm with your insurance company that this provider accepts your insurance.

Locations and Appointments

NYU Langone Heart Rhythm Center

403 East 34th Street, 4th Floor
New York, NY 10016

NYU Langone Medical Associates - Chelsea

160 West 26th Street
New York, NY 10001

NYU Electrophysiology

560 1st Avenue, 5th Floor
New York, NY 10016


cellular mechanisms, cardiac arrhythmias , sudden death, atrial fibrillation

Research Summary

Atrial fibrillation (AF) is the most common clinical arrhythmia seen and results in significant morbidity and mortality. As a result, there is tremendous interest in understanding the mechanisms leading to and supporting AF. Clinically, AF starts with ectopic atrial activity originating from the pulmonary veins or the body of the left atrium. Should these atrial beats coincide with a vulnerable atrial substrate able to support multiple wavelet reentry, AF results. While there are currently no good animal models to study ectopic atrial activity, an atrial tachy-paced model is used to study the atrial changes resulting from high frequency electrical activity. While this model recapitulates many of the features of clinical AF, it also has numerous shortcomings. More recently, it has been observed that following congestive heart failure, atrial structures dilate and are thus susceptible to AF initiation. This model is more closely related to human pathophysiology. We are using a rabbit model of myocardial infarction to study the cellular changes induced by pressure overload atrial dilation.

At the cellular level, we are investigating the electrophysiologic alterations underlying abnormal automaticity and triggered activity. Failing cardiac tissues undergo remodeling of their ion handling proteins characterized by up or down regulation of protein expression. In general, these changes tend to amplify subthreshold electrical events into triggered activity. While the mechanisms behind ventricular ectopy have become well characterized, those of the atrium are less well understood. Among the differences between atrial and ventricular cells is the presence of IP3 receptors in atrial tissue. These calcium-releasing receptors are up regulated in failing atrium and may play a role in both triggered activity within the atrial free wall and abnormal automaticity from spontaneously firing cells within the pulmonary veins. Using confocal microscopy and patch clamp techniques, in a collaboration with the laboratory of Dr. William Coetzee and Michael Artman, we simultaneously measure subcellular calcium transients and sarcolemmal membrane currents. Interactions between excitation-contraction mechanisms and IP3 calcium release could form the basis of new atrial specific therapeutic targeting.

These focus areas and their associated publications are derived from PubMed and the MeSH term library. *
represents one publication
*Due to PubMed processing times, the most recent publications may not be reflected in the timeline.

  • Chorin, Ehud; Wadhwani, Lalit; Magnani, Silvia; Dai, Matthew; Shulman, Eric; Nadeau-Routhier, Charles; Knotts, Robert; Bar-Cohen, Roi; Kogan, Edward; Barbhaiya, Chirag; Aizer, Anthony; Holmes, Douglas; Bernstein, Scott; Spinelli, Michael; Park, David S; Stefano, Carugo; Chinitz, Larry A; Jankelson, Lior

    Heart rhythm. 2020 Sep ; 17(9):1425-1433

  • Long term survival and local control outcomes from single dose targeted intraoperative radiotherapy during lumpectomy (TARGIT-IORT) for early breast cancer: TARGIT-A randomised clinical trial

    Vaidya, J S; Bulsara, M; Baum, M; Wenz, F; Massarut, S; Pigorsch, S; Alvarado, M; Douek, M; Saunders, C; Flyger, H L; Eiermann, W; Brew-Graves, C; Williams, N R; Potyka, I; Roberts, N; Bernstein, M; Brown, D; Sperk, E; Laws, S; Sutterlin, M; Corica, T; Lundgren, S; Holmes, D; Vinante, L; Bozza, F; Pazos, M; Le, Blanc-Onfroy M; Gruber, G; Polkowski, W; Dedes, K J; Niewald, M; Blohmer, J; McCready, D; Hoefer, R; Kelemen, P; Petralia, G; Falzon, M; Joseph, D J; Tobias, J S

    British medical journal. BMJ (Clinical research ed.). 2020 Aug 19; ):m2836

  • Chorin, Ehud; Peterson, Connor; Kogan, Edward; Barbhaiya, Chirag; Aizer, Anthony; Holmes, Douglas; Bernstein, Scott; Schole, Michael; Duraiswami, Harish; Spinelli, Michael; Park, David; Chinitz, Larry; Jankelson, Lior

    American journal of cardiology. 2020 Aug 15; 129:25-29

Read All Publications (33)

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