Ira M. Jacobson, MD

  • Specialty: Gastroenterology
  • Language: English
  • Phone: 212-263-0474
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About Me

I became fascinated with biology as a child, when my elementary school teacher showed me the teeming life in a drop of pond water through a microscope. My ambition to become a doctor arose from medicine’s ideal combination of science and helping others.

Much later, I decided to specialize in gastroenterology because of the diversity of conditions doctors manage in this field, and the scientific and technologic advances that characterized its dynamic growth early in my medical career. I was particularly fascinated with the liver because of the central role it plays in hundreds of the body’s vital processes.

I devote much of my clinical time caring for people who have liver disease, including viral hepatitis and other liver conditions. For patients who require liver transplantation, I work closely with our surgeons at the NYU Langone Transplant Institute. I am also actively involved in the broader specialty of gastroenterology and gastrointestinal endoscopy, including upper gastrointestinal endoscopy and colonoscopy.

As the director of hepatology at NYU Langone Health, I aim to expand and enhance the clinical, research, and educational programs in liver disease and mentor the exceptional group of hepatologists here. It’s an honor to work with such a wonderful hepatology team and to provide patient care alongside world-class experts in medicine, surgery, pathology, radiology, oncology, and other specialties.

The primary source of gratification in my professional life is patient care. I enjoy meeting my patients and their families and hearing about their lives, and I pride myself on spending as much time with my patients as they need. While I focus on their specific conditions, I do so in the broad context of their overall health.

I place an emphasis on accessibility in my practice—my patients can contact me at any time through secure electronic communication. I also emphasize clear communication during office visits. We live in an era of “evidence-based medicine,” but existing medical evidence must sometimes be combined with clinical experience and judgment for the best approach to care. To do this, I provide individualized care and focus on each person and how he or she is unique.

For more than 30 years, I have participated in hundreds of clinical trials on antiviral therapy for viral hepatitis, including hepatitis B and C, and I have also led a number of them. These studies have remarkably improved our ability to treat people with these conditions, including the capacity to cure nearly all patients who have hepatitis C. I have authored and coauthored more than 250 scientific papers, chapters, and reviews on these and other topics. I continue to be involved in studies on viral hepatitis, and am also involved in studies examining treatments for other liver diseases, such as fatty liver disease and primary biliary cholangitis.

I am a fellow of several major organizations, including the American College of Physicians, the American Gastroenterological Association, the American Association for the Study of Liver Diseases, and the American College of Gastroenterology, and a member of the European Association for the Study of the Liver. Recently, I was honored to be elected to a fellowship at the Royal College of Physicians in the United Kingdom. I am a past president of the New York Society for Gastrointestinal Endoscopy and the New York Gastroenterological Association.

Conditions and Treatments

viral hepatitis, gallstone disease, fatty liver, liver diseases, colonoscopy, autoimmune hepatitis, primary biliary cirrhosis, colon cancer screening, liver tumor, bile duct abnormalities, endoscopy
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  • Professor, Department of Medicine
  • Director, Hepatology
Board Certifications
  • American Board of Internal Medicine (Gastroenterology), 1985
  • American Board of Internal Medicine - Internal Medicine, 1982
Education and Training
  • Fellowship, Harvard Medical School, Gasteoenterology, 1984
  • Residency, University of California, San Francisco, School of Medicine, Internal Medicne, 1982
  • MD from Columbia University, 1979

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Locations and Appointments

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  • Aetna
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    • Medicare Part A
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NYU Gastroenterology Associates

530 First Avenue, HCC 7H
New York, NY 10016



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NYU Hepatology Associates

530 1st Avenue, Suite 4J
New York, NY 10016

Research My Research


Hepatitis, Fatty liver disease, Priimary biliary choangitis, primary sclerosing cholangitis

Academic Contact

Academic office

530 First Avenue


New York, NY 10016





Clinical Trials and Research Studies

  • A Phase 2 Randomized Double-Blind Placebo-Controlled Study Evaluating the Safety and Efficacy of Selonsertib GS-0976 GS-9674 and Combinations in Subjects with Bridging (F3) Fibrosis or Compensated Cirrhosis (F4) due to Nonalcoholic Steatohepatitis

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  • A single-center pilot study of the use of hepatitis C positive donors for hepatitis C negative lung transplant recipients with post-transplant treatment with Mavyret

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  • An 8-week dose ranging open label randomized Phase 2 study with an 18-week extension to evaluate the safety and efficacy of MBX-8025 in subjects with Primary Biliary Cholangitis (PBC) and an inadequate response to or intolerance to ursodeoxycholic ac

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View All Research Studies (3)


  • Vermehren, Johannes; Park, James S; Jacobson, Ira; Zeuzem, Stefan

    Journal of hepatology. 2018 Nov 15; 69(5):1178-1187

  • Jacobson, Ira M

    Gastroenterology. 2018 Oct 12; 155(4):969-971

  • Non-alcoholic fatty liver disease (NAFLD) and alcoholic fatty liver disease (AFLD): The impact of alcohol consumption and metabolic syndrome on mortality [Meeting Abstract]

    Younossi, Z M; Stepanova, M; Ong, J; Yilmaz, Y; Duseja, A K; Eguchi, Y; El, Kassas M; Fernandez, M; George, J; Jacobson, I M; Bugianesi, E; Wong, V W S; Arrese, M; De, Ledinghen V; Romero-Gomez, M; Mendez-Sanchez, N; Ahmed, A; Wong, R J; Papatheodoridis, G V; Serfaty, L; Mathurin, P; Younossi, I; Nader, F; Ziayee, M; Afendy, A

    Hepatology. 2018 October; Conference:(69th):801A-802A

Read All Publications (414)

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