Credentials
Positions
- Professor, Department of Anesthesiology, Perioperative Care, and Pain Medicine at NYU Grossman School of Medicine
- Professor, Department of Cell Biology at NYU Grossman School of Medicine
- Director, Cardiothoracic Anesthesia
Board Certifications
- American Board of Anesthesiology - Anesthesiology, 2006
Education and Training
- Residency, NYU Medical Center, Anesthesiology, 2004
- Residency, New York Presbyterian - Weill Cornell Medical Center, Anesthesiology, 2001
- MD from Medical Academy Of Magdeburg, 1985
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Edit profileInsurance Plans Accepted
This provider accepts the following insurance plans.
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Aetna
- Aetna HMO
- Aetna Indemnity
- Aetna Medicare
- Aetna POS
- Aetna PPO/EPO
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Agewell
- Agewell
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Amidacare
- Amidacare
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Blue Cross Blue Shield
- Empire BCBS
- Empire BCBS Top Tier
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Cigna
- Cigna EPO/POS
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ElderPlan
- ElderPlan
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Emblem
- Emblem Select Care Exchange
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Empire Blue Cross Blue Shield
- Empire Blue Cross Blue Shield EPO
- Empire Blue Cross Blue Shield HMO
- Empire Blue Cross Blue Shield HealthPlus
- Empire Blue Cross Blue Shield Indemnity
- Empire Blue Cross Blue Shield MediBlue
- Empire Blue Cross Blue Shield POS
- Empire Blue Cross Blue Shield PPO
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Fidelis
- Fidelis Child Health
- Fidelis Exchange
- Fidelis Medicaid
- Fidelis Medicare
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GHI
- GHI CBP
- GHI HMO
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HIP
- HIP Access I
- HIP Access II
- HIP Child Health
- HIP EPO/PPO
- HIP HMO
- HIP Medicaid
- HIP Medicare
- HIP POS
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Hamaspik Choice
- Hamaspik Choice Medicare DSNP
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Healthfirst
- Healthfirst
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Hotel Trades
- Hotel Trades
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Humana
- Humana Medicare
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Local 1199
- Local 1199 PPO
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Longevity Health Plan
- Longevity Health Plan Medicare
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MagnaCare
- MagnaCare PPO
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Medicaid
- NY Medicaid
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Medicare
- Medicare
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MetroPlus
- MetroPlus Child Health
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MultiPlan/PHCS
- MultiPlan/PHCS PPO
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NYS Health Insurance Plan
- The Empire Plan
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Oscar
- Oscar
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Oxford
- Oxford Freedom
- Oxford Liberty
- Oxford Medicare
- Oxford Metro
- Oxford Mosaic
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Progyny Inc.
- Progyny Inc
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Railroad Medicare
- Railroad Medicare
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Senior Whole Health
- Senior Whole Health
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Tricare
- Tricare
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UHC
- UnitedHealthcare EPO
- UnitedHealthcare HMO
- UnitedHealthcare Medicare
- UnitedHealthcare POS
- UnitedHealthcare PPO
- UnitedHealthcare Top Tier
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United Healthcare
- UHC Medicare Complete Choice Regional PPO
- United Healthcare Compass Exchange /CareCore / Charter
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VNS
- Visiting Nurse Service (VNS) Medicare
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Village Caremax
- Village Caremax
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WTC Health Program
- WTC Health Program
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WellCare
- WellCare Medicare
Michael Schlame, MD does not accept insurance.
Locations and Appointments
NYU Anesthesia Associates
550 First Avenue, Suite 605, New York, NY 10016
Research My Research
Interests
cardiomyopathy, lipid biochemistry, mitochondria
Research Summary
Barth syndrome is a hereditary cardiomyopathy that also affects skeletal muscles, growth, and neutrophils. The mutated gene (tafazzin) is homologous to a conserved family of phospholipid acyltransferases. Children with Barth syndrome are deficient in the mitochondrial phospholipid cardiolipin, suggesting that the primary defect of the disease may indeed be found in phospholipid metabolism and may specifically affect the phospholipids of mitochondria. We want to study the mechanism by which tafazzin mutation causes cardiomyopathy and skeletal muscle disease. First, we want to identify the enzymatic function of tafazzin. We will identify the intracellular localization of tafazzin, its impact on lipid composition, and its mechanism of action. Second, we want to examine the effect of tafazzin on structure and function of mitochondria. Since mitochondrial dysfunction is a plausible etiology of cardiomyopathy and skeletal muscle weakness, we will analyze mitochondrial ultrastructure and oxidative phosphorylation in cell lines with tafazzin deletion. Third, we want to explore a Drosophila model of Barth syndrome, which was created in our laboratory. We will study lipid metabolism, muscle physiology, morphology, and mitochondrial ultrastructure in fruit flies with tafazzin deletion. The Drosophila model will also be used for cardiac studies since flies contain a contractile fluid pumping organ that shares conserved features of cardiogenesis with all heart-forming creatures, including humans. The project will provide insight into the pathologic mechanism of a unique disease, which presents a novel pathway from lipid defect(s) to cardio-skeletal myopathy. Such information may be useful for the development of new therapeutic approaches to cardiomyopathy and skeletal muscle disease.
Academic Contact
Academic office
560 First Avenue
Fifth Floor
New York, NY 10016
Phone
Research Interests Timeline
Publications
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Liang, Zhuqing; Ralph-Epps, Tyler; Schmidtke, Michael W; Lazcano, Pablo; Denis, Simone W; Balážová, Mária; Teixeira da Rosa, Nevton; Chakkour, Mohamed; Hazime, Sanaa; Ren, Mindong; Schlame, Michael; Houtkooper, Riekelt H; Greenberg, Miriam L
Scientific reports. 2024 Jun 25; 14(1):14633
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Liang, Zhuqing; Ralph-Epps, Tyler; Schmidtke, Michael W; Lazcano, Pablo; Denis, Simone W; Balážová, Mária; Teixeira J, Nevton da Rosa; Chakkour, Mohamed; Hazime, Sanaa; Ren, Mindong; Schlame, Michael; Houtkooper, Riekelt H; Greenberg, Miriam L
Scientific reports. 2024 May 20; 14(1):11497
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Ren, Mindong; Xu, Yang; Phoon, Colin K L; Erdjument-Bromage, Hediye; Neubert, Thomas A; Schlame, Michael
Journal of biological chemistry. 2023 Oct ; 299(10):105241