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Bo Shopsin at [NYU Langone Health]
NYU Langone Provider

Bo Shopsin, MD, PhD

NYU Langone Provider
  • Specialty: Infectious Diseases
  • Language: English

Positions
Board Certifications
  • American Board of Internal Medicine (Infectious Disease), 2006
Education and Training
  • Fellowship, New York University, Infectious Diseases, 2006
  • Residency, New York University, Internal Medicine, 2004
  • MD from New York University, 2001
  • PhD from New York University, 2000

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Interests

genomics, immunology, microbiology

Research Summary

Our lab is focused on understanding the adaptive changes in S. aureus that take place during infection. An integrated approach is used that incorporates new technologies to detect low abundance variants in pooled bacterial populations, traditional bacterial and evolutionary genetics, and molecular population genetic analysis. A special focus of these studies is on the identification of within-host variation in the agr locus, a global regulator of virulence in S. aureus. agr mutants are attenuated for virulence in animal models of infection, and the majority of clinical isolates have a functional agr locus. However, agr-defective strains are frequently recovered from patients with a variety of hospital-acquired infections, suggesting that the occurrence of these strains may be favored under certain in vivo conditions. This work is motivated by practical questions in infectious diseases (such as the best use of antimicrobials that target agr and virulence), as well as more basic yet closely intertwined questions, such as how to explain the alterations that are responsible for adaptive changes atdifferent stages of S. aureus infections.

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Academic Contact

Lab Website

These focus areas and their associated publications are derived from PubMed and the MeSH term library. *
represents one publication
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*Due to PubMed processing times, the most recent publications may not be reflected in the timeline.

  • A Phase III Randomized Double-blind Placebo-controlled Multicenter Study in Adults to Determine the Safety Efficacy and Immunogenicity of AZD1222 a Non-replicating ChAdOx1 Vector Vaccine for the Prevention of COVID-19

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  • A Phase 1/2 Placebo-Controlled Randomized Observer-Blind Dose-Finding Study to Describe the Safety Tolerability Immunogenicity and Potential Efficacy of SARS CoV 2 RNA Vaccine Candidates Against COVID 19 in Healthy Adults

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  • Phlebotomy of Healthy Adults for the Purpose of Evaluation and Validation of Immune Response and Microbiology Assays

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View All Research Studies (3)

Read All Publications (46)

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