Non-Hodgkin Lymphoma in Adults

We use molecular and genetic tests to diagnose non-Hodgkin lymphoma. This form of cancer arises in the body’s lymphatic system—the network of vessels, nodes, and other organs that drain excess fluid from tissues and help the body fight infections. These tests enable our hematologists, or blood cancer specialists, to create a personalized treatment plan for you. Approaches may include chemotherapy, targeted medications, stem cell transplantation, and radiation therapy. We can also determine whether you may benefit from new therapies being studied in clinical trials.

Clinical Trials and Research Studies

Phase 1

Phase 1 Open-Label Multicenter Dose Escalation Study of mRNA-2752 a Lipid Nanoparticle Encapsulating mRNAs Encoding Human OX40L IL-23 and IL-36? for Intratumoral Injection Alone and in Combination with Immune Checkpoint Blockade

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Phase 6

A Phase II/III randomized study of R-miniCHOP with or without oral azacitidine (CC-486) in participants age 75 years or older with newly diagnosed diffuse large B cell lymphoma Grade IIIb Follicular Lymphoma transformed lymphoma and high-grade B-cell lymphomas with MYC and BCL2 and/or BCL6 rearrangements

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Phase 1

An Open Label First in Human (FIH) Phase 1 Trial of LVGN6051 as Single Agent and in Combination with Keytruda (pembrolizumab) in Advanced or Metastatic Malignancy

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Phase 2

Single-arm open label phase II study of MBG453 (sabatolimab) added to FDA approved Hypomethylating agents of investigator s choice (IV/SC/Oral) for patients with intermediate high or very high risk myelodysplastic syndrome (MDS) as per IPSS-R criteria (US multi-center) (STIMULUS MDS-US)

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