In 1982, Dr. Herbert Lepor was a co-author of the landmark publication study describing nerve-sparing anatomic radical retropubic prostatectomy, which greatly improves oncological and functional outcomes.
Dr. Lepor initiated a prospective Institutional Review Board–approved outcomes study in October 2000. The study examined factors such as survival and disease recurrence as well as functional outcomes such as lower urinary tract symptoms, urinary continence, and sexual function following nerve-sparing anatomic radical retropubic prostatectomy.
Since then, more than 2,000 men have been enrolled into what has become the longest longitudinal study of men undergoing radical prostatectomy. More than 90 percent of men enrolled in this study were reported alive 10 years after radical prostatectomy, and aging exhibits effects independent of functional outcomes.