Dimitris G. Placantonakis, MD, PhD

  • Specialty: Neurosurgery
  • Languages: English, French, Greek
  • Phone: 212-263-2441

About Me

When I was in high school, I became fascinated with the genetic code built into our DNA and the exquisite complexity of the brain. Early on, I knew that I wanted to care for patients who had disorders of the brain and work to improve treatment options to increase people’s comfort during and after treatment.

As a neurosurgeon–scientist, I have dedicated my career to surgically treating people who have brain tumors, researching brain tumor biology, and designing new therapies. I specialize in surgery to remove gliomas, glioblastomas, pituitary adenomas, meningiomas, and brain metastases. Using minimally invasive techniques, I am able to minimize the impact of surgery on the brain.

Through my work designing and running clinical trials, I am also able to offer people opportunities to participate in research aimed at advancing new treatments, techniques, and medications that can prolong people’s lives. I am dedicated to advancing the scientific knowledge of complex brain tumors, and I train and mentor future scientists and physician–scientists.

I am honored to have been recognized by Super Doctors and The Leading Physicians of the World many times. It’s gratifying to receive this recognition, but I most cherish the opportunity to make a difference in the lives of my patients and their families. A brain cancer diagnosis can be the most difficult and stressful period in a person’s life. I am privileged to be a part of the solution and grateful to be able to form powerful emotional bonds with my patients and their families during these difficult times.


Conditions and Treatments

brain tumor, brain cancer, glioma, astrocytoma, pituitary adenoma, brain metastasis, meningioma, craniopharyngioma, endoscopic surgery, brain mapping, CNS lymphoma, carcinomatous meningitis, pineal tumor, pituitary tumor, lumbar disc disease, spinal narrowing, hydrocephalus, brain biopsy
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Credentials

Positions
  • Assistant Professor, Department of Neurosurgery
  • Dir Neurosurgical Laboratory for Stem Cell Resch
Board Certifications
  • American Board of Neurological Surgery - Neurological Surgery, 2013
Education and Training
  • Residency, Memorial Sloan-Kettering Cancer Center, Neurosurgery, 2010
  • Residency, Cornell University Medical College, Neurosurgery, 2010
  • Fellowship, Memorial Sloan-Ketteriing Cancer Center, 2008
  • MD from New York University, 2003
  • PhD from New York University, 2003
Departments

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NYU Neurosurgery Associates

530 1st Avenue, Suite 8R
New York, NY 10016

Research My Research

Interests

Glioblastoma stem cells, human embryonic stem cells, glioma biology, gliomagenesis, glioma therapeutics, cancer, imaging, molecular, cellular, & translational neuroscience

Research Summary

Dr. Placantonakis obtained his MD/PhD degree in Neuroscience from NYU School of Medicine and completed a postdoctoral fellowship in human embryonic stem cell biology with Drs. Lorenz Studer and Viviane Tabar at Memorial Sloan-Kettering. He was also trained in Neurosurgery at Weill Cornell Medical College and Memorial Sloan-Kettering. At NYU, he is a tenure-track physician-scientist dividing his time between his neurosurgical practice and the laboratory. Dr. Placantonakis has an interest in the treatment of gliomas and brain tumors in general. The Neurosurgical Laboratory for Stem Cell Research, which is headed by Dr. Placantonakis, studies stem cell biology in the context of glioma, a malignant brain tumor. We adapt human embryonic stem cell and genetic technologies to model oncogenic processes, with the goal of understanding the early steps in glioma formation and developing translational applications, such as high-throughput drug screening and biomarker identification. Furthermore, we use genetic approaches and patients' tissue to generate models for high-grade gliomas, with emphasis on the role of stem cells in pathogenesis and new therapeutic approaches that directly target them. Our ultimate goal is to translate our laboratory findings to new therapies and diagnostic tests for patients with glioma.

Dr. Placantonakis' laboratory is funded by the National Institutes of Health (NIH) and private foundations.

Academic Contact

Academic office

540-562 First Avenue

Eighth Floor

New York, NY 10016

Phone

212-263-2441

Lab Website

Research Interests Timeline

These focus areas and their associated publications are derived from PubMed and the MeSH term library.
represents one publication
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Publications

  • Modeling HSV-1 Latency in Human Embryonic Stem Cell-Derived Neurons

    Pourchet, Aldo; Modrek, Aram S; Placantonakis, Dimitris G; Mohr, Ian; Wilson, Angus C Pourchet, Aldo; Modrek, Aram S; Placantonakis, Dimitris G; Mohr, Ian; Wilson, Angus C
    Pathogens. 2017 Jun 8. 6 (2): ?-?

  • LOW-GRADE ASTROCYTOMA CORE MUTATIONS IN IDH1, P53 AND ATRX COOPERATE TO BLOCK DIFFERENTIATION OF HUMAN NEURAL STEM CELLS VIA EPIGENETIC REPRESSION OF SOX2 [Meeting Abstract]

    Modrek, Aram; Golub, Danielle; Khan, Themasap; Prado, Jod; Bowman, Christopher; Deng, Jingjing; Zhang, Guoan; Rocha, Pedro; Raviram, Ramya; Lazaris, Harris; Kader, Michael; Dhaliwal, Joravar; Chi, Andrew; Golfinos, John; Tsirigos, Aristotelis; Zagzag, David; Snuderl, Matija; Skok, Jane; Neubert, Thomas; Modrek, Aram; Golub, Danielle; Khan, Themasap; Prado, Jod; Bowman, Christopher; Deng, Jingjing; Zhang, Guoan; Rocha, Pedro; Raviram, Ramya; Lazaris, Harris; Kader, Michael; Dhaliwal, Joravar; Chi, Andrew; Golfinos, John; Tsirigos, Aristotelis; Zagzag, David; Snuderl, Matija; Skok, Jane; Neubert, Thomas; Placantonakis, Dimitris
    Neuro-oncology. 2017 JUN. 19: 35-35
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  • Notch signaling regulates metabolic heterogeneity in glioblastoma stem cells

    Bayin, N Sumru; Frenster, Joshua D; Sen, Rajeev; Si, Sheng; Modrek, Aram S; Galifianakis, Nataliya; Dolgalev, Igor; Ortenzi, Valerio; Illa-Bochaca, Irineu; Khahera, Anadjeet; Serrano, Jonathan; Chiriboga, Luis; Zagzag, David; Golfinos, John G; Doyle, Werner; Tsirigos, Aristotelis; Heguy, Adriana; Chesler, Bayin, N Sumru; Frenster, Joshua D; Sen, Rajeev; Si, Sheng; Modrek, Aram S; Galifianakis, Nataliya; Dolgalev, Igor; Ortenzi, Valerio; Illa-Bochaca, Irineu; Khahera, Anadjeet; Serrano, Jonathan; Chiriboga, Luis; Zagzag, David; Golfinos, John G; Doyle, Werner; Tsirigos, Aristotelis; Heguy, Adriana; Chesler, Mitch; Barcellos-Hoff, Mary Helen; Snuderl, Matija; Placantonakis, Dimitris G
    Oncotarget. 2017 May 23. ?-?
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Read All Publications (50)