News from NYU Langone Health
Surgeons at NYU Langone Health transplant a genetically modified pig kidney into a patient
WBFO-FM (Buffalo, NY)
Surgeons at NYU Langone Health have transplanted a genetically modified pig kidney into a patient. This operation is the first to be conducted as part of a formal, FDA-approved study to test the viability of such organs. The procedure aims to solve the chronic shortage of human organs for transplantation. While previous, less formal attempts to transplant pig organs have failed, researchers remain hopeful that this structured approach could eventually lead to a successful solution.
Also reporting was: KFF Health News, Becker's Hospital Review, Vision Monday
11/02/2025
NYU Langone physiologist weighs in on the weighted vest trend
WBNG-TV (Johnson City, NY)
Heather A. Milton, MS, RCEP, CSCS, an exercise physiologist supervisor at NYU Langone’s Sports Performance Center, provides her expert take on the trend of using weighted vests for workouts. She confirms that wearing a vest can enhance a cardio workout by raising your heart rate and is also beneficial for resistance training, helping to build muscle and bone health. However, Milton cautions that data does not support the common claim that simply walking in a vest for short periods improves bone density. For those who want to try it, she advises starting with a vest that is about 5% of your body weight and is adjustable.
11/04/2025
Is Diabetes Reversible? Doctors Reveal What the Latest Research Says
Prevention
An article explores the concept of diabetes remission, clarifying that while 'reversal' is a misnomer, remission is possible for prediabetes and sometimes type 2 diabetes. Priya Jaisinghani, MD, an endocrinologist at NYU Langone Health, explains that prediabetes remission involves improving insulin release and resistance through diet, exercise, and potentially metformin. She also notes that type 2 diabetes remission can be achieved via medication, lifestyle changes, or bariatric surgery. Type 1 diabetes, an autoimmune condition, generally does not go into remission, though new treatments like FDA-approved Lantidra offer hope for managing it.
11/04/2025
New Study Reveals That This Type of Exercise May Fight Depression As Well As Build Muscle
Women's Health
A new study published in Medicine & Science in Sports & Exercise found that strength training can reduce symptoms of depression, similar to quiet rest. Thea Gallagher, PsyD, Director, Wellness Programs, clinical associate professor, Department of Psychiatry at NYU Grossman, who was not involved in the study, suggests that the sense of accomplishment from lifting weights can contribute to improved mood. The research indicates that both aerobic and resistance training may impact brain structure, blood flow, and inflammation, potentially lowering depression risk. Strength training might also uniquely influence insulin-like growth factor-1.
Also reporting was: Aol
11/04/2025
11 warning signs of a heart attack you might be missing
FODMAP Everyday
The article outlines 11 often-missed warning signs of a heart attack, emphasizing that symptoms extend beyond the typical 'Hollywood' chest pain. It highlights profound fatigue, unexplained jaw/neck/back pain, shortness of breath, and indigestion as critical indicators. The piece notes that a cold sweat, dizziness, and arm pain (right or left) are also significant. Lawrence Phillips, MD, cardiologist, medical director, Outpatient Clinical Cardiology, FGP and associate professor of medicine at NYU Langone Health, explains that dizziness can signal an issue with the heart's electrical system. The article stresses the importance of recognizing these 'atypical' signs, especially for women, and advises calling 911 if in doubt, as 'time is muscle' in cardiology.
11/04/2025
Candel Therapeutics Advances Cancer Immunotherapy Innovations
Investors Hangout
Candel Therapeutics will present cancer immunotherapy advancements at the SITC Annual Meeting, including a pivotal phase 3 trial for CAN-2409 in prostate cancer. Daniel Sterman, MD, Thomas and Suzanne Murphy Professor of Pulmonary and Critical Care Medicine, and division director, Pulmonary, Critical Care & Sleep Medicine, and director of the Pulmonary Oncology Program, will present phase 2a trial data on CAN-2409 for non-small cell lung cancer, revealing significant immune activation and improved survival rates in non-squamous NSCLC patients. Candel will also highlight its AI-driven enLIGHTEN™ Discovery Platform for designing efficient immunotherapies.
11/03/2025
American Journal of Managed Care
Joshua K. Sabari, MD, assistant professor, Department of Medicine, Division of Hematology and Medical Oncology, and director of High Reliability Organization Initiatives, Perlmutter Cancer Center, discusses the critical role of clinical pathways in personalizing oncology care. He explains how these pathways streamline and universalize care across large health systems like NYU Langone Health, ensuring consistent standards for patients. Sabari envisions the future of precision oncology leveraging artificial intelligence platforms to better guide and sequence systemic therapeutic options. This approach would allow for individualized treatment strategies based on a patient's unique history and genetic makeup, moving beyond current guidelines to optimize care.
11/03/2025
Centers Health Care Enhances Rehabilitation Programs for Residents
Investors Hangout
Centers Health Care expanded its collaboration with NYU Langone's Rusk Rehabilitation, extending their onsite-physician model from Boro Park Center to Amsterdam Nursing Home. This initiative provides residents with direct access to specialized rehabilitation care, aiming to improve recovery and reduce hospital readmissions. Matthew Glenn, MD, Clinical Instructor, Department of Rehabilitation Medicine, NYU Langone Hospital—Brooklyn, emphasized personalized treatment plans. The program, which has benefited over 1,000 patients at Boro Park Center, offers physical, occupational, and speech therapies, fostering independence and enhancing quality of life for residents.
11/03/2025
Fully maximizing bearing diameter may reduce dislocation risk in fixed-bearing THA
Orthopedics Today
Research presented at the American Association of Hip and Knee Surgeons Annual Meeting indicates that fully maximizing bearing diameter in primary fixed-bearing total hip arthroplasty may reduce dislocation risk. Matthew S. Hepinstall, MD, orthopedic surgeon at NYU Langone Health, Co- Director of Center for Computer Navigation and Robotic Orthopedic Surgery, reported on a retrospective review of 8,607 THAs, finding no dislocations in 835 patients with maximized bearing diameters, compared to over 1% in the non-maximized group. The study identified head size as the most influential factor for dislocation odds, with bearing diameter significantly impacting dislocation rates independently of surgical approach or technology.
11/04/2025
RTOG Foundation Launches New Clinical Trial Investigating Lu-DOTA-TATE
SCIENMAG
The RTOG Foundation launched the MOMENTUM-1 trial (RTOG 3523), a phase II study evaluating ^177Lu-Dotatate for progressive intracranial meningiomas. This multicenter trial randomizes 153 participants to receive either the investigational agent or standard-of-care medical therapy, with a crossover option. Erik P. Sulman, MD, PhD, adjunct professor, Department of Radiology and principal investigator, emphasized the critical need for novel systemic therapies for recurrent meningiomas. ^177Lu-Dotatate is a targeted radiotherapeutic that delivers localized radiation to tumor cells. The study aims to define a new standard of care, potentially improving progression-free survival for patients with aggressive meningiomas.
Also reporting was: Bioengineering
11/03/2025
Can you take Eliquis less than 12 hours apart?
SingleCare
Nieca Goldberg, MD, cardiologist and clinical associate professor, Department of Medicine, the Leon H. Charney Division of Cardiology, advises that aspirin, omega-3 supplements, clopidogrel, and ticagrelor heighten bleeding risk when taking Eliquis. The piece outlines standard twice-daily, 12-hour dosing, cautions against doses taken too close together, and details missed-dose steps. Overdose management and reversal options, including andexanet alfa and activated charcoal, are described. Higher-risk populations and warning signs of bleeding or stroke are highlighted, with added context from Gail Clifford, MD.
11/03/2025
GLP-1 RAs Appear Safe, Effective for Patients with T2D on Dialysis
MedCentral
At Obesity Week 2025, a national observational study co-authored by Holly F. Lofton, MD, clinical associate professor in surgery at NYU Grossman School of Medicine, with presenting author Babak J. Orandi, MD, PhD, transplant surgeon and obesity medicine specialist at NYU Langone’s Weight Management Program and the NYU Langone Transplant Institute, found GLP-1 receptor agonist exposure among more than 150,000 dialysis patients with type 2 diabetes linked to greater weight and BMI reductions, lower mortality (aHR 0.77), and higher transplant waitlisting (aHR 1.66). Safety signals were neutral except increased diabetic retinopathy risk.
11/03/2025
High Fluid Rates May Raise Inflammation Risk in Pancreatitis
Medscape
At the ACG 2025 meeting on 27 October 2025, researchers from NYU Langone Health reported that higher early intravenous fluid rates in acute pancreatitis were associated with greater odds of persistent or new SIRS but lower odds of BUN elevation. In a prospective cohort across 22 sites, each 1 mL/kg/h increase raised SIRS risk yet reduced BUN rise. Findings suggest sicker patients received more fluids, and observational design limits causality.
11/04/2025
Secukinumab Tops Ustekinumab for PsA Functional Improvement
Medscape
A randomized, double-blind trial presented at the American College of Rheumatology 2025 Annual Meeting found secukinumab more effective than ustekinumab for psoriatic arthritis patients who failed TNF inhibitors. Odds of improvement on the Health Assessment Questionnaire-Disability Index were over three times higher with secukinumab. Jose U. Scher, MD, Steere Abramson Professor of Medicine, NYU Langone Orthopedic Hospital, and director of the NYU Colton Center for Autoimmunity and the NYU Langone Health Psoriatic Arthritis Center, commented that IL-17 blockade remains a more potent option for joint disease. He noted the trial's unique head-to-head design and use of a patient-reported functional endpoint, which is relevant for payers.
11/04/2025
Epic connects 17 health systems to federal data network
Becker's Hospital Review
NYU Langone Health joined the federally supported TEFCA exchange via Epic Nexus in October, as one of 17 Epic customers going live. The connection enables standardized nationwide exchange of electronic health data under a 2022 federal framework. Epic says more than 1,000 hospitals are now connected through TEFCA. Other participating systems include Henry Ford Health, Michigan Medicine, Sanford Health, Valley Health System, and One Brooklyn Health.
11/04/2025
Genetic Testing Can’t Produce Designer Babies, Says Ethicist
Medscape
Art Caplan, PhD, the Drs. William F. and Virginia Connolly Mitty Professor of Bioethics, Department of Population Health, Division of Medical Ethics, warns that Nucleus Genomics’ whole-genome testing and embryo-selection services overpromise and lack scientific certainty. He notes limits of current polygenic risk prediction, the role of environment and development, and raises eugenics concerns over trait selection. He cites pricing around $1200 for individual testing and up to $6000 for embryos, advising patients and prospective parents to avoid such services until stronger evidence emerges.
11/03/2025
The 'No. 1' Ice Cream Brand in America Just Recalled a Top Product In 30 States
The Healthy
Häagen-Dazs initiated a recall of its Chocolate Dark Chocolate Mini Bars across 30 states due to undeclared wheat, a significant allergen. Dreyer’s Grand Ice Cream, Inc. issued the recall for specific batch codes sold at Kroger and Giant Eagle. The company acknowledged potential serious health risks for individuals with wheat allergies. NYU Langone highlights that one third of Americans avoid gluten due to Celiac disease and sensitivities. Consumers are advised to dispose of or return affected products for a full refund.
11/04/2025
