News from NYU Langone Health

MRNA Vaccine Responses Correlate With Delayed Pancreatic Cancer Recurrence. (OBR)

OBR (4/8) “With three years’ follow-up, an adjuvant, individualized mRNA vaccine continues to induce immune responses associated with reduced risk of disease recurrence in certain patients with resectable pancreatic cancer,” and, “commenting on the results, Paul E. Oberstein, MD, associate professor, Department of Medicine, Division of Hematology and Medical Oncology, Perlmutter Cancer Center, said that ‘these longer-term data suggest that, for some patients, a customized vaccine can induce long-lasting changes that may protect against pancreatic cancer recurrence.’”

Linvoseltamab Elicits Deep Responses In Late-Stage R/R Multiple Myeloma. (OncLive)

OncLive (4/8) “Linvoseltamab elicited a high response rate and showcased an acceptable safety profile in patients with relapsed/refractory multiple myeloma, including difficult-to-treat subsets, according to data from the phase 1/2 LINKER-MM1 study (NCT03761108) presented during the 2024 AACR Annual Meeting,” and “after the presentation, Faith E. Davies, MD, professor, Department of Medicine, Division of Hematology and Medical Oncology, Perlmutter Cancer Center, further discussed the data and what it means for this population.”
MedPage Today (4/8) “New treatment options for relapsed/refractory myeloma are needed, said invited discussant Faith E. Davies, MD, professor, Department of Medicine, Division of Hematology and Medical Oncology, Perlmutter Cancer Center,” who also said, “We’re gaining a new problem, which is how do we treat triple-class-refractory patients.”

Cancer Is Rising Among The Young. Study Suggests It’s Because Their Cells Are Aging Faster. (STAT)

Paywall* STAT (4/7)* Jiyoung Ahn, PhD, professor, Departments of Population Health, and Medicine, Perlmutter Cancer Center, who was not involved in the study, said, “I think the findings are important. But the association needs to be replicated. And, also, the mechanism needs to be figured out.”

ACC: Study Shows J&J’s Abiomed Pump Reduces Deaths After Widowmaker Heart Attacks.

Fierce Biotech “In an accompanying NEJM editorial, Sunil Rao, MD, professor, Department of Medicine, the Leon H. Charney Division of Cardiology, said the success in the latest results could be linked to either changes in the study’s design or the types of patients enrolled, as well as differences in the devices or any combination of those factors.”

Long-Awaited RCT Data Show Survival Benefit With Impella CP: DanGer Shock. (ReachMD)

ReachMD (4/9) “In an editorial accompanying the NEJM paper, Sunil Rao, MD, professor, Department of Medicine, the Leon H. Charney Division of Cardiology, says the findings represent a milestone for the field,” writing, “These striking results mark the first treatment strategy to show a benefit in patients with AMICS since the SHOCK trial, published in 1999, established percutaneous coronary intervention as the cornerstone of treatment.”

The Solar Eclipse Can Damage Your Eyes: ‘Do Not Underestimate The Power Of The Sun’. (WPIX-TV New York)

WPIX-TV New York (4/8) “‘When you are in an area that is in full totality, you can actually take off your glasses shielding your eyes and take a glimpse at the sun because the moon is blocking the rays from the sun,’ said Nitish Mehta, MD, clinical assistant professor, Department of Ophthalmology, NYU Langone Health Eye Center.”

Mapping The Mind: Advances In Understanding Speech Production. (Forbes)

Forbes (4/8) “A recent NYU Grossman School of Medicine study analyzed hundreds of brain-mapping recordings from 16 patients preparing for epilepsy surgery,” where “researchers observed the impact of stimulation on the speech production of a particular brain region, particularly the time it took for the stimulation to affect speech.”

Jayden Daniels-Commanders Rumors Grow As 2024 NFL Draft Looms. (New York Post)

The New York Post (4/8) “There had been some concern on social media about” LSU quarterback Jayden Daniels “last month as a photo made the rounds showing him to have a lump the size of a golf ball hanging off his throwing elbow,” but “Laith M. Jazrawi, professor, Department of Orthopedic Surgery, Division of Sports Orthopedic Surgery, told The Post that this was hardly a cause for concern.”

Can Standardized Training Improve EFAST Learning? (AuntMinnie)

AuntMinnie (4/8) “In her presentation, Jacqueline Gomberg, MD, clinical instructor, the Ronald O. Perelman Department of Emergency Medicine, showed that emergency medical staff expressed more positive attitudes toward performing eFAST exams after participating in training that takes less than two hours to attend,” saying, “Everyone … said that the session was very helpful and that it was likely to change their clinical practice, which is ultimately our goal in the end.”

Urology’s Inconvenient Truth: Impact Of Climate Change. (Medscape)

Paywall* Medscape (4/9)* “The use of telemedicine can help urologists cut down on their carbon footprint, according to Stacy Loeb, MD, professor, Departments of Urology and Population Health, Perlmutter Cancer Center,” citing “a meta-analysis by researchers from the University of Southern California in Los Angeles that showed telemedicine consistently reduced greenhouse gas emissions.”

Three Distinct MS Subtypes Identified. (Medscape)

Paywall* Medscape (4/9)* “Multiple sclerosis (MS) has three distinct subtypes based on immune markers in patient’s blood, each with slightly different disease trajectories and responses to therapy, a new study suggested,” and “commenting on the findings for Medscape Medical News, Kimberly A. O’Neill, MD, clinical instructor, Department of Neurology, noted that people with MS can have ‘a broad variety of disease course and outcomes ranging from mild to a very severe and life-altering disease course.’”

‘Good Problem To Have’: FDA Approvals Arrive ‘All At Once’ In Bladder Cancer. (OBR)

OBR (4/2) “Scot Niglio, MD, assistant professor, Department of Medicine, Division of Hematology and Medical Oncology, Perlmutter Cancer Center, discusses this rapidly evolving landscape” of treating bladder cancer “and how newly approved therapies have already become the ‘backbone’ of urothelial carcinoma care.”
Also reporting is UroToday (4/8).

The Role Of AI In Medical Education: Embrace It Or Fear It? (KevinMD)

The KevinMD (4/8) “NYU Grossman School of Medicine has run with this idea and has fully embraced the idea of precision learning from AI by incorporating a ‘precision education’ tool” where each “medical student is offered a personalized medical education, with an AI algorithm tailoring subject matter and content format.”

Can A Total Solar Eclipse Make You Sick? Experts Weigh In On ‘Eclipse Sickness’ Claims. (Fox News)

Fox News (4/8) “NYU Langone Medical Center professor Marc K. Siegel, MD, clinical professor, Department of Medicine, Division of General Internal Medicine, told Fox News Digital that he believes there is a medical basis for some of the adverse health effects,” explaining “that flicker vertigo – which is vertigo caused by flickering bright lights – may be a reason for recent ailments.”
In a separate embedded segment with Fox News (4/8) “Fox News medical contributor Marc K. Siegel, MD, clinical professor, Department of Medicine, Division of General Internal Medicine, spoke “on what to know about bird flu and why it is important to not look directly at the solar eclipse without proper glasses.”
Also reporting is Fox News (4/8).

AI Reveals Huge Amounts Of Fraud In Medical Research. (DW News)

DW News (3/29) Arthur L. Caplan, PhD, the Drs. William F. and Virginia Connolly Mitty Professor, Department of Population Health, Division of Medical Ethics, discusses the revelation of fraudulent data that has been published, and then retracted in medical journals, reminding viewers that “the real test of science is replication, not the first publication.”