Harvey I. Pass, MD

  • Specialty: Thoracic Surgery
  • Language: English
  • Phone: 212-731-5414
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About Me

My father was a general practitioner and my biggest inspiration in pursuing a career in medicine. Initially, I chose to specialize in cardiac and thoracic surgery because of all the exciting developments in the field at that time. But I decided to pursue thoracic oncology after I realized that the real challenge was in understanding and treating thoracic cancer as a surgeon and scientist.

As director of general thoracic surgery and chief of thoracic oncology at NYU Langone’s Perlmutter Cancer Center, I specialize in treating people with lung cancer and mesothelioma, a rare cancer related to asbestos exposure. I also treat people who have other benign and malignant diseases of the chest. I am widely recognized as a thought leader in the management of thoracic malignancies, and patients come to me because of my reputation as a thoughtful and talented thoracic surgeon.

As a physician, I value close communication with my patients. I am always available over text or email when a patient or family member has a question or needs guidance. I strongly believe that it is important to consider all possible scenarios to help a patient make an important decision, so that they trust I am doing what is best for them.

Our multidisciplinary team of specialists at NYU Langone includes thoracic surgeons, medical oncologists, pulmonary physicians, interventional radiologists, and radiation oncologists who meet regularly to discuss the best treatment options for each patient. We take a highly personalized approach to treating patients and use the most advanced treatments, including minimally invasive techniques and robotic surgery, which can offer quicker recovery, less pain, and a shorter hospital stay.

I feel lucky to have previously been named the second division chief of thoracic oncology at the National Cancer Institute, Bethesda, where I ran my own laboratory, wrote my own clinical trials, and had the privilege of being mentored by Steven Rosenberg, MD, PhD—the father of modern immunotherapy. I have trained with the best surgeons in the field, who taught me the importance of curiosity, novelty, and the pursuit of scientific discovery. Thanks to my early career path, I am able to use my skills and experience to be a resource for my patients and colleagues and provide the best care and mentorship in the field of thoracic surgery and oncology.

During my career, I have actively worked to advance treatment and knowledge about mesothelioma and lung cancer, and I am passionate about conducting research for early detection of thoracic malignancies to ensure a greater chance for cure. Through specimens contributed by patients before, during, and after surgery, my laboratory studies thoracic cancer to possibly not only develop new strategies for treatment but also find signatures in the blood to detect cancer early on.

Mentorship of young surgeons and scientists is a big part of my life. This is why I am at NYU Langone, where all of these aspects of being a doctor are not only encouraged, but expected, so that the most insightful, safe, and compassionate care is delivered to our patients.

I am a member of the American Association for Thoracic Surgery, the Cardiothoracic Surgery Network, the General Thoracic Surgical Club, and the Society of Thoracic Surgeons. I have coauthored 6 textbooks on lung cancer and thoracic oncology and published more than 550 peer-reviewed manuscripts to guide physicians in the field.

In recognition of my contribution to the diagnosis and treatment of mesothelioma, I have received the Wagner Medal from the International Mesothelioma Interest Group, the Pioneer Award from the Mesothelioma Applied Research Foundation, and the American Association for Cancer Research’s Landon Foundation-AACR Innovator Award for International Collaboration in Cancer Research. I have also been named in Castle Connolly’s series of “America’s Top Doctors,” “America’s Top Doctors for Cancer,” and “Top Doctors in the New York Metro Area” for many consecutive years.


Conditions and Treatments

thoracic cancer, thoracic disease, lung cancer, mesothelioma, thymus cancer, mediastinal tumor, esophageal cancer, non-small cell lung cancer, pericardial disease, achalasia, lung metastasis, esophageal disorder, pancoast tumor, pericardial effusion, malignant mesothelioma, robotic assisted surgery, lung carcinoma, lobectomy, bronchoscopy, upper gastrointestinal endoscopy, solitary fibrous tumor, electromagnetic navigation bronchoscopy, soft tissue sarcoma, minimally invasive surgery, neuroendocrine tumor of the lung, gastroesophageal reflux disease, diagnostic bronchoscopy, salivary gland tumor, esophageal surgery, mucoepidermoid carcinoma of the lung, cancer surgery, neuroendocrine tumor of the lung, thoracic surgery, pleural effusion, lung biopsy, adenoid cystic carcinoma of the lung, endoscopic ultrasound, small cell lung cancer, therapeutic bronchoscopy
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Credentials

Positions
  • Stephen E. Banner Professor of Thoracic Oncology, Department of Cardiothoracic Surgery
  • Professor, Department of Surgery
  • Director, General Thoracic Surgery, NY Harbor Healthcare VA Hospital
  • Chief, Division of Thoracic Surgery, NYU School of Medicine
  • Vice Chair of Research, Department of Cardiothoracic Surgery
Board Certifications
  • American Board of Thoracic Surgery - Thoracic Surgery, 1983
Education and Training
  • Fellowship, National Institute of Health, Cardio-Thoracic Surg, 1986
  • Residency, Medical Univ. of South Carolina, Cardio-Thoracic Surg, 1982
  • Residency, University of Mississippi, Surgery, 1980
  • MD from Duke University, 1973

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NYU Cardiothoracic Surgery Associates

160 East 34th Street, 8th Floor
New York, NY 10016

Research My Research

Interests

osteopontin, fibulin 3, lung cancer, microRNA, proteomics, mesothelioma, asbestos, screening, early detection, thoracic oncology

Research Summary

The Thoracic Oncology laboratory investigates biomarker signatures for lung cancer and mesothelioma both in tissue and in the blood for discovery and validation. This work is supported by the National Cancer Institute Early Detection Research Network since 2005. Specifically our interests include the use of plasma osteopontin for the early detection and diagnosis of lung cancer, and studies of the role of osteopontin isoforms in order to increase specificity. Osteopontin is also being investigated for the prognosis of early lung cancer and mesothelioma, and we have demonstrated that plasma osteopontin can stratify resected Stage I lung cancers by their disease free survival. In mesothelioma, modeling of clinical parameters with plasma osteopontin can predict which patients will have long term survival. Other mesothelioma biomarkers include Fibulin 3 which to date has the highest sensitivity and specificty published for the diagnosis of mesothelioma using blood based biomarkers. Fibulin 3 levels in blood as well as in pleural effusions can differentiate mesothelioma from individuals with benign effusions, from others with non mesothelioma malignant effusions, and from patients exposed to asbestos but who do not have mesothelioma. A large validation study using an asbestos exposed cohort of individuals in Santiago Chile funded by the NCI will commence in the third quarter of 2015.  MicroRNA studies, using NanoString are also the subject of an NCI awarded RO1 to Drs. Pass and Carlo Croce for the differential diagnosis of the solitary pulmonary nodule, and these studies are ongoing. The Thoracic Oncology Laboratory collaborates with Industry for the discovery and validation of biomarkers. Biomarker profiles for lung cancer and mesothelioma using  Slow Off Rate Modified Aptamers (SOMAmers) in collaboration with Somalogic, Boulder CO, have been published and are in final validation phases. Other proteomic based plasma biomarker studies for lung cancer have been reported in collaboration with Integrated Diagnostics.

Academic Contact

Academic office

530 First Avenue

Skirball 9V

New York, NY 10016

Phone

212-731-5414

Fax

212-263-2246

Research Interests Timeline

These focus areas and their associated publications are derived from PubMed and the MeSH term library.
represents one publication
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Clinical Trials and Research Studies

  • A Phase II Open-Label Multicenter Single-Arm Study to Investigate the Efficacy and Safety of Atezolizumab as neoadjuvant and adjuvant therapy in Patients with Stage IB II or IIIA resectable and untreated non-small cell lung cancer

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  • A Randomized Phase III Study of Sublobar Resection (SR) versus Stereotactic Ablative Radiotherapy (SAbR) in High Risk Patients with Stage I Non-Small Cell Lung Cancer (NSCLC)

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View All Research Studies (2)

Publications

Read All Publications (633)