Harvey I. Pass, MD

  • Specialty: Thoracic Surgery
  • Language: English
  • Phone: 212-731-5414
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About Me

 


Conditions and Treatments

thoracic cancer, thoracic disease, lung cancer, mesothelioma, thymus cancer, mediastinal tumor, esophageal cancer, non-small cell lung cancer, achalasia, pericardial disease, lung metastasis, esophageal disorder, pancoast tumor, solitary fibrous tumor, adenoid cystic carcinoma of the lung, upper gastrointestinal endoscopy, gastroesophageal reflux disease, electromagnetic navigation bronchoscopy, lobectomy, minimally invasive surgery, pleural effusion, esophageal surgery, salivary gland tumor, diagnostic bronchoscopy, small cell lung cancer, lung carcinoma, cancer surgery, soft tissue sarcoma, thoracic surgery, neuroendocrine tumor of the lung, lung biopsy, pericardial effusion, endoscopic ultrasound, malignant mesothelioma, therapeutic bronchoscopy, mucoepidermoid carcinoma of the lung, robotic assisted surgery, neuroendocrine tumor of the lung, bronchoscopy
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Credentials

Positions
  • Stephen E. Banner Professor of Thoracic Oncology, Department of Cardiothoracic Surgery
  • Professor, Department of Surgery
  • Chief, Division of Thoracic Surgery, NYU School of Medicine
  • Director, General Thoracic Surgery, NY Harbor Healthcare VA Hospital
  • Vice Chair of Research, Department of Cardiothoracic Surgery
Board Certifications
  • American Board of Thoracic Surgery - Thoracic Surgery, 1983
Education and Training
  • Fellowship, National Institute of Health, Cardio-Thoracic Surg, 1986
  • Residency, Medical Univ. of South Carolina, Cardio-Thoracic Surg, 1982
  • Residency, University of Mississippi, Surgery, 1980
  • MD from Duke University, 1973

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NYU Cardiothoracic Surgery Associates

160 East 34th Street, 8th Floor
New York, NY 10016

Research My Research

Interests

osteopontin, fibulin 3, lung cancer, microRNA, proteomics, mesothelioma, asbestos, screening, early detection, thoracic oncology

Research Summary

The Thoracic Oncology laboratory investigates biomarker signatures for lung cancer and mesothelioma both in tissue and in the blood for discovery and validation. This work is supported by the National Cancer Institute Early Detection Research Network since 2005. Specifically our interests include the use of plasma osteopontin for the early detection and diagnosis of lung cancer, and studies of the role of osteopontin isoforms in order to increase specificity. Osteopontin is also being investigated for the prognosis of early lung cancer and mesothelioma, and we have demonstrated that plasma osteopontin can stratify resected Stage I lung cancers by their disease free survival. In mesothelioma, modeling of clinical parameters with plasma osteopontin can predict which patients will have long term survival. Other mesothelioma biomarkers include Fibulin 3 which to date has the highest sensitivity and specificty published for the diagnosis of mesothelioma using blood based biomarkers. Fibulin 3 levels in blood as well as in pleural effusions can differentiate mesothelioma from individuals with benign effusions, from others with non mesothelioma malignant effusions, and from patients exposed to asbestos but who do not have mesothelioma. A large validation study using an asbestos exposed cohort of individuals in Santiago Chile funded by the NCI will commence in the third quarter of 2015.  MicroRNA studies, using NanoString are also the subject of an NCI awarded RO1 to Drs. Pass and Carlo Croce for the differential diagnosis of the solitary pulmonary nodule, and these studies are ongoing. The Thoracic Oncology Laboratory collaborates with Industry for the discovery and validation of biomarkers. Biomarker profiles for lung cancer and mesothelioma using  Slow Off Rate Modified Aptamers (SOMAmers) in collaboration with Somalogic, Boulder CO, have been published and are in final validation phases. Other proteomic based plasma biomarker studies for lung cancer have been reported in collaboration with Integrated Diagnostics.

Academic Contact

Academic office

530 First Avenue

Skirball 9V

New York, NY 10016

Phone

212-731-5414

Fax

212-263-2246

Research Interests Timeline

These focus areas and their associated publications are derived from PubMed and the MeSH term library.
represents one publication
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Clinical Trials and Research Studies

  • A Phase II Open-Label Multicenter Single-Arm Study to Investigate the Efficacy and Safety of Atezolizumab as neoadjuvant and adjuvant therapy in Patients with Stage IB II or IIIA resectable and untreated non-small cell lung cancer

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  • A Randomized Phase III Study of Sublobar Resection (SR) versus Stereotactic Ablative Radiotherapy (SAbR) in High Risk Patients with Stage I Non-Small Cell Lung Cancer (NSCLC)

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View All Research Studies (2)

Publications

Read All Publications (624)