Orrin Devinsky, MD

  • Specialties: Epilepsy, Neurology
  • Language: English
  • Phone: 646-558-0803

About Me

I fell in love with science and biology as a young boy. In college, I spent several years conducting basic science research in immunology, but I found myself wanting a more direct connection with people.

In medical school, famed neurologist Norman Geschwind introduced me to the magic of the brain and the mind. At that time, the field of neurology covered only a few disorders that were treatable by doctors. Epilepsy was one such disorder in which doctors had an opportunity to help patients. It also offered a window into how the brain works.

I am fortunate to be the director of NYU Langone’s Comprehensive Epilepsy Center, where we have two of the world’s finest epilepsy surgeons: Drs. Howard Weiner and Werner Doyle. We have a large, dedicated team of epileptologists and neuropsychologists who have collaborated to pioneer several techniques, including responsive neurostimulation therapy, multistage epilepsy surgery, and multiple subpial transection. 

We often treat patients who were told by other medical institutions that they couldn’t benefit from treatment. Our professionals are experts in many diverse areas, from new medication development and diagnostic procedures, to scientific studies of cognitive and behavioral functions, to surgical procedures. These specialists are bound together by a deep, shared sense of teamwork and compassion.

At the center, our philosophy isn’t simply “no seizures, no side effects”; it involves finding a treatment balance that allows children and adults with epilepsy to lead full, high-quality lives. 

Conditions and Treatments

epilepsy, tuberous sclerosis


  • Professor, Department of Neurology
  • Professor, Department of Neurosurgery
  • Professor, Department of Psychiatry
  • Chief of Service, NYU Epilepsy Service
Board Certifications
  • American Board of Psychiatry & Neurology - Neurology, 1987
Education and Training
  • Fellowship, National Institute of Health, 1988
  • Residency, New York Presbyterian - Weill Cornell Medical Center, Neurology, 1986
  • MD from Harvard Medical School, 1982

Locations and Appointments

60 Insurance Plans Accepted
  • Aetna HMO
  • Aetna Indemnity
  • Aetna Medicare
  • Aetna POS
  • Aetna PPO/EPO
  • Affinity
  • Affinity Exchange- Essential
  • Cigna EPO/POS
  • Cigna PPO
  • ElderPlan
  • Empire Blue Cross Blue Shield EPO
  • Empire Blue Cross Blue Shield HMO
  • Empire Blue Cross Blue Shield Indemnity
  • Empire Blue Cross Blue Shield MediBlue
  • Empire Blue Cross Blue Shield POS
  • Empire Blue Cross Blue Shield PPO
  • Empire Blue Cross Blue Shield Pathways, Enhanced
  • Fidelis Child Health
  • Fidelis Exchange
  • Fidelis Family Health
  • Fidelis Medicaid
  • Fidelis Medicare
  • HIP Access I
  • HIP Access II
  • HIP Child Health
  • HIP Family Health
  • HIP Medicaid
  • HIP Medicare
  • HealthSmart (WTC)
  • Humana Medicare
  • Local 1199 PPO
  • MagnaCare PPO
  • MetroPlus Child Health
  • MetroPlus Exchange Plans
  • MetroPlus Family Health
  • MetroPlus Medicaid
  • MetroPlus Medicare
  • MultiPlan/PHCS PPO
  • NYS Empire Plan
  • Oxford Exchange
  • Oxford Freedom
  • Oxford Liberty
  • Oxford Medicare
  • UPN Elite
  • United Exchange- Compass
  • UnitedHealthcare Community & State Plan
  • UnitedHealthcare EPO
  • UnitedHealthcare HMO
  • UnitedHealthcare Medicare
  • UnitedHealthcare POS
  • UnitedHealthcare PPO
  • UnitedHealthcare Top Tier
  • Visiting Nurse Service (VNS) Medicare
  • WellCare Child Health
  • WellCare Family Health
  • WellCare Medicare
*Insurance listed above may not be accepted at all office locations. Please confirm prior to each visit. The information presented here may not be complete or may have been changed.
NYU Langone Comprehensive Epilepsy Center

223 East 34th Street
New York, NY 10016

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My Research

The Comprehensive Epilepsy Center, directed by Orrin Devinsky, M.D., offers multidisciplinary evaluation, medical treatment and surgical intervention for epilepsies by a team of epileptologists, neuropsychologists, neurosurgeons, psychiatrists, and other specially trained support personnel. The major goal of the Center is to provide comprehensive care to people with epilepsy. Routine and advanced diagnostic studies, 10 clinical pharmacologic trials, and a variety of therapeutic interventions are carried out to better understand the disorder and improve treatment.

Dr. Devinsky and his co-investigators are presently conducting studies of several investigational antiepileptic medications such as topiramate, tiagabine, lamotrigine, vigabatrin, oxcarbazepine, and remacemide, as well as vagal nerve stimulator implantation. The Comprehensive Epilepsy Center offers 16 inpatient video-EEG-monitored beds in a specialized Epilepsy Monitoring Unit. Each bed has the capacity for 64 channels of EEG data with on-line computer analysis for 24-hour seizure and spike detection.

Preoperative neuropsychological assessment, invasive monitoring including depth and subdural electrode studies, intraoperative electrocorticography and functional localization of language, motor and sensory areas permits precise surgical approaches to remove epileptic tissue while sparing necessary brain areas.


  • Cortical feature analysis and machine learning improves detection of "MRI-negative" focal cortical dysplasia

    Ahmed, Bilal; Brodley, Carla E; Blackmon, Karen E; Kuzniecky, Ruben; Barash, Gilad; Carlson, Chad; Quinn, Brian T; Doyle, Werner; French, Jacqueline; Devinsky, Orrin; Thesen, Thomas
    Epilepsy & behavior. 2015 May. 48: 21-28

  • Thalamic functional connectivity predicts seizure laterality in individual TLE patients: Application of a biomarker development strategy

    Barron, Daniel S; Fox, Peter T; Pardoe, Heath; Lancaster, Jack; Price, Larry R; Blackmon, Karen; Berry, Kristen; Cavazos, Jose E; Kuzniecky, Ruben; Devinsky, Orrin; Thesen, Thomas
    NeuroImage: Clinical. 2015. 7: 273-280

  • Treatment Resistant Epilepsy in Autism Spectrum Disorder: Increased Risk for Females

    Blackmon, Karen; Bluvstein, Judith; MacAllister, William S; Avallone, Jennifer; Misajon, Jade; Hedlund, Julie; Goldberg, Rina; Bojko, Aviva; Mitra, Nirmala; Giridharan, Radha; Sultan, Richard; Keller, Seth; Devinsky, Orrin
    Autism research. 2015 Jun. ?-?

Read All Publications (657)