Seth J. Orlow, MD, PhD

  • Specialty: Pediatric Dermatology
  • Language: English
  • Phone: 212-263-5889

About Me

I was born in Brooklyn, and although I lived elsewhere during college and residency training, I consider myself a lifelong New Yorker. While getting my MD and PhD in molecular pharmacology from Albert Einstein College of Medicine in the Bronx, I realized I was especially fascinated by the field of dermatology. I loved taking care of children when I rotated through pediatrics as a medical student, so I chose to combine these interests and specialize in pediatric and adolescent dermatology.

I arrived at NYU Langone in 1990, joining one of the leading dermatology departments in the world. Whether treating a newborn or a college student, I want to do everything I can to help my patients and to support their families, while always balancing the benefits and risks of a particular treatment.

In my research, I have worked to determine the risks associated with certain birthmarks and skin growths, such as hemangiomas, and have collaborated with molecular geneticists to identify genetic changes that cause congenital skin conditions. I’ve also worked to improve how we treat eczema and psoriasis in children and teenagers. In 2003, I received a Lifetime Achievement Award from the American Skin Association. 

Conditions and Treatments

atopic dermatitis, eczema, acne, birthmark, psoriasis, hemangioma, skin cancer, genetic skin diseases, melanoma, hair diseases, mole, skin diseases, pigmentation disorders, fungal infection, lichen planus, hair loss, vitiligo, seborrheic dermatitis, squamous cell cancer, basal cell cancer, skin cancer screening
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  • Samuel Weinberg Professor of Pediatric Dermatology, Ronald O. Perelman Department of Dermatology
  • Professor, Department of Cell Biology
  • Professor, Department of Pediatrics
  • Dermatology Director Program in Cutaneous Biology and NYU Center of Excellence in Cancers of the Skin
  • Chair Ronald O Perelman Department of Dermatology
Board Certifications
  • American Board of Dermatology (Pediatric Dermatology), 2004
  • American Board of Dermatology - Dermatology, 1990
Education and Training
  • Fellowship, Yale - New Haven Medical Center, Pediatric Dermatology, 1990
  • Residency, Yale - New Haven Medical Center, Dermatology, 1989
  • MD from Albert Einstein College Of Med, 1986
  • PhD from Albert Einstein College Of Med, 1986

Locations and Appointments

2 Insurance Plans Accepted
  • HealthSmart (WTC)
  • UnitedHealthcare Top Tier
*Insurance listed above may not be accepted at all office locations. Please confirm prior to each visit. The information presented here may not be complete or may have been changed.
NYU Dermatologic Associates

530 1st Avenue, Suite 7R
New York, NY 10016


Phone: 212-263-5889


530 1st Avenue
New York, New York 10016


Phone: 212-263-5889

NYU Dermatologic Associates

240 East 38th Street, 12th Floor
New York, NY 10016


Phone: 212-263-5015

Welcome back!

As a returning patient for this doctor, please schedule an appointment using your MyChart at NYU Langone account.

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“My research has improved treatments for eczema and psoriasis in children and teenagers.”

Seth J. Orlow, PhD, MD Pediatric Dermatologist

My Research

1. Development of novel therapeutics for the treatment of a number of cancers including melanoma and multiple myeloma, as well as unraveling pathways underlying chemoresistance in these tumors. To do so, we utilize small molecule screening of already-approved drugs ("drug repositioning") and of natural products combined with molecular and cellular techniques. 2. Understanding the cell biology of melanin synthesis and deposition in the skin, hair and eyes, including the processing and trafficking of tyrosinase, the rate-limiting enzyme in melanin production, as well as the pathogenesis of various forms of oculocutaneous albinism that diminish pigmentation. 3. Elucidating the pathogenesis of vitiligo, in which melanocytes in the skin are destroyed, including the role of endoplasmic reticulum stress and the unfolded protein response.


  • Microbes and atopic dermatitis: The Yin and Yang of barrier and immune dysfunction [Review]

    Cohen, BE; Orlow, SJ
    Hong Kong journal of dermatology & venereology = Xianggang pifu ji qingbing xue zazhi. 2016 SPR. 24 (1): 17-23

  • Segmental stiff skin syndrome (SSS): A distinct clinical entity

    Myers, Kathryn L; Mir, Adnan; Schaffer, Julie V; Meehan, Shane A; Orlow, Seth J; Brinster, Nooshin K
    Journal of the American Academy of Dermatology. 2016 Mar 2. ?-?

  • Alternative Systemic Treatments for Vitiligo: A Review

    Cohen, Brandon E; Elbuluk, Nada; Mu, Euphemia W; Orlow, Seth J
    American journal of clinical dermatology. 2015 Dec . 16 (6): 463-474

Read All Publications (243)