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Glenn I. Fishman, MD

  • Specialty: Cardiology
  • Language: English

About Me

Conditions and Treatments

Conditions
  • ventricular arrhythmia
  • atrial fibrillation
  • atrial flutter
  • Brugada syndrome
  • dilated cardiomyopathy
  • heart muscle disease
  • hypertrophic cardiomyopathy
  • long QT syndrome
  • myocardial disease
  • rapid heartbeat
  • slow heartbeat
  • ventricular arrhythmia
  • ventricular fibrillation
  • ventricular tachycardia
  • chronic venous insufficiency
  • heart attack
  • occlusive vascular disease
  • cerebrovascular disorder
  • inflammation of the membrane surrounding the heart
  • metabolic syndrome
  • heart disease
  • fainting
  • angina
  • high blood pressure disorder
  • claudication
  • arteriosclerosis
  • ischemic cardiomyopathy
  • atherosclerosis
  • abnormal heart rhythms
  • myocarditis
  • high cholesterol level
  • chest pain
  • renal artery stenosis
  • aortic valve disease
  • congestive heart failure
  • peripheral vascular disease
  • aortic valve insufficiency
  • mitral regurgitation
  • cardiac disease in pregnancy
  • carotid artery disease
  • obesity
  • endothelial dysfunction
  • coronary heart disease
  • rheumatic heart disease
  • heart murmur
  • lipid disorder
  • aortic valve stenosis
  • mitral valve prolapse
  • mitral valve stenosis
  • lipid metabolism
  • carotid stenosis
  • heart throbbing
  • acute coronary syndrome
  • inflammation of the heart valve
  • sarcoidosis
  • heart tumor
  • renal vascular disorder
  • arterial occlusive disease

Credentials

Positions
  • William Goldring Professor of Medicine, Department of Medicine
  • Professor, Department of Neuroscience and Physiology
  • Professor, Department of Biochemistry and Molecular Pharmacology
  • Vice Chair for Research, Department of Medicine
  • Director, Leon H. Charney Division of Cardiology
Board Certifications
  • American Board of Internal Medicine (Cardiovascular Disease), 1989
  • American Board of Internal Medicine - Internal Medicine, 1986
Education and Training
  • Fellowship, Albert Einstein College Hospital, Molecular Cardiology, 1990
  • Fellowship, Columbia-Presbyterian Medical Ctr., Cardiology, 1988
  • Residency, Massachusetts General Hospital, Medicine, 1986
  • Residency, Massachusetts General Hospital, Medicine, 1984

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Insurance Plans Accepted

This provider accepts the following insurance plans.

  • Aetna
    • Aetna HMO
    • Aetna Indemnity
    • Aetna Medicare
    • Aetna POS
    • Aetna PPO/EPO
  • Cigna
    • Cigna EPO/POS
    • Cigna PPO
  • Emblem
    • Emblem Select Care Exchange
  • Empire Blue Cross Blue Shield
    • Empire Blue Cross Blue Shield EPO
    • Empire Blue Cross Blue Shield HMO
    • Empire Blue Cross Blue Shield HealthPlus
    • Empire Blue Cross Blue Shield HealthPlus Essential
    • Empire Blue Cross Blue Shield Indemnity
    • Empire Blue Cross Blue Shield MediBlue
    • Empire Blue Cross Blue Shield POS
    • Empire Blue Cross Blue Shield PPO
    • Empire Blue Cross Blue Shield Pathways, Enhanced
  • GHI
    • GHI CBP
    • GHI HMO
  • HIP
    • HIP Access I
    • HIP Access II
    • HIP Child Health
    • HIP EPO/PPO
    • HIP Essential
    • HIP HMO
    • HIP Medicaid
    • HIP Medicare
    • HIP POS
View All Accepted Plans This list of insurances changes regularly, and insurance plans listed may not be accepted at all office locations for this provider. Before your appointment, please confirm with your insurance company that this provider accepts your insurance.

Research My Research

Interests

cardiovascular biology, cardiovascular development, cardiovascular genetics, cardiac electrophysiology and arrhythmias, immunology, metabolism

Research Summary

My laboratory focuses on several facets of cardiovascular biology and disease. First, we are interested in the formation and function of the heart's specialized cardiac conduction system (CCS). This complex network comprises pacemaking cells that establish the normal rhythmicity of the heart, as well as rapidly conducting His-Purkinje cells that facilitate highly synchronized excitation of the working myocardium.

Our studies of the conduction system utilize genetically engineered mouse models that specifically visualize various components of the network. Gene profiling of microdissected CCS tissue is then employed to identify the molecular signature of these specialized cells. A complementary approach for gene discovery using murine embryonic stem cells is being developed, whereby such pluripotent cells can be differentiated into specific components of the CCS under defined cultured conditions.

A second area of investigation includes studies of arrhythmia mechanisms, focusing especially on the dysregulation of gap junction channels and the associated abnormalities in impulse propagation. These studies include a multiple of strategies that range from molecular and biochemical through genetically engineered murine models with site-specific mutations in connexin genes, which encode the gap junction channel proteins. Our laboratory was the first to demonstrate the essential role of gap junction channels in cardiac rhythmicity, using conditional knockout approaches. Current studies are focused on defining the role of post-translational regulation of connexins during normal gap junction formation and in response to pathologic stimuli that lead to abnormal gap junction remodeling.

Research Interests Timeline

These focus areas and their associated publications are derived from PubMed and the MeSH term library. *
represents one publication
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*Due to PubMed processing times, the most recent publications may not be reflected in the timeline.

Publications

Read All Publications (107)

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