NIH Awards $12 Million Grant to NYU Langone Medical Center’s Gbenga Ogedegbe, MD, to Examine Racial, Ethnic, and Socioeconomic Risk Factors of Stroke

Ogedegbe and Colleagues to Establish NIH-Funded Center for Stroke Disparities Solution

NYU Langone Medical Center is pleased to announce that Gbenga Ogedegbe, MD, MS, MPH, professor and director, Division of Health & Behavior in the Department of Population Health, has received a $12 million, five-year grant from The National Institute of Neurological Disorders and Stroke (NINDS) of the National Institutes of Health (NIH), which will be used to create a new Center for Stroke Disparities Solutions in New York City.

The grant is part of a $40-million initiative of the NINDS Stroke Prevention/Intervention Research Program (SPIRP), to examine racial, ethnic, and socioeconomic risk factors of stroke and to eliminate disparities in stroke incidence in the U.S. Despite the progress made in the reduction of stroke mortality for the general U.S. population in the past decade, blacks and Hispanics continue to experience worse stroke-related outcomes than whites.

Created to address these disparities, the Center is a collaboration between NYU Langone, Columbia University Medical Center, five stroke centers and primary care practices within New York City's Health and Hospital Corporation (HHC); SUNY Downstate Medical Center, and a home healthcare organization – the Visiting Nurses of New York. Dr. Ogedegbe will co-lead the Center, along with Olajide Williams, MD, associate professor of clinical neurology and chief of staff, Department of Neurology at Columbia University Medical Center.

The goal of the Center is to reduce stroke disparities with a particular focus on prevention of recurrent stroke among minority populations in New York City, and ultimately the U.S.  via the: 1) development and implementation of innovative, cost-effective, evidence-based interventions targeted at aggressive management of hypertension among stroke survivors in community-based primary care practices within HHC; and 2) dissemination of novel, culturally-tailored stroke health education in faith-based and other community-based organizations in NYC. To this end, the Center will launch three targeted projects:

  • The first project is a comparative effectiveness trial of the effects of home blood pressure (BP) telemonitoring alone versus that intervention plus telephonic nurse case management, on BP reduction and prevention of recurrent stroke among 450 black and Hispanic stroke survivors with uncontrolled hypertension.
  • A second project, The Stroke Community Transitions Intervention, will evaluate the effectiveness of a culturally-tailored transition care program delivered by nurse practitioners and community health workers in improving BP control, functional outcomes, and quality of life among 650 homebound stroke survivors. It will address the vulnerable period when stroke survivors transition from the hospital to their home. 
  • Lastly, the team will evaluate the effectiveness of a culturally tailored 12 minute video to increase stroke literacy among adults in Black and Hispanic churches across NYC. The film is intended to boost awareness about the need to call 911 immediately after the onset of even seemingly minor stroke symptoms.

Additionally, the Center will train and mentor under-represented minority junior faculty, preparing them for successful academic careers in behavioral and translational sciences targeting reduction of stroke disparities, and ensuring that a diverse and highly trained workforce to lead the nation’s biomedical and behavioral stroke research agenda.

“This grant is important because it will allow us, for the very first time, to evaluate a multi-level approach to reducing disparities in stroke on a population-based scale via a consortium of academic centers and a municipal healthcare system,” said Dr. Ogedegbe. “If proven effective, this model can then be adopted for reduction of disparities in outcomes from other cardiovascular diseases.”

This project is supported by the National Institute Of Neurological Disorders And Stroke of the National Institutes of Health under Award Number U54NS081765. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.