Glenn Fishman at [NYU Langone Medical Center]

Glenn I. Fishman, MD

  • Specialty: Cardiology
  • Language: English

About Me

Conditions and Treatments

abnormal heart rhythms

Credentials

Positions
  • William Goldring Professor of Medicine, Department of Medicine
  • Professor, Department of Biochemistry and Molecular Pharmacology
  • Professor, Department of Neuroscience and Physiology
  • Vice Chair Research Dept of Medicine
  • Dir Division of Cardiology
Board Certifications
  • American Board of Internal Medicine (Cardiovascular Disease), 1989
  • American Board of Internal Medicine - Internal Medicine, 1986
Education and Training
  • Fellowship, Albert Einstein College Hospital, Molecular Cardiology, 1990
  • Fellowship, Columbia-Presbyterian Medical Ctr., Cardiology, 1988
  • Residency, Massachusetts General Hospital, Medicine, 1986
  • Residency, Massachusetts General Hospital, Medicine, 1984
  • MD from Stanford University, 1983

Locations and Appointments

48 Insurance Plans Accepted
  • Aetna HMO
  • Aetna Indemnity
  • Aetna Medicare
  • Aetna POS
  • Aetna PPO/EPO
  • Affinity
  • Affinity Exchange- Essential
  • Cigna EPO/POS
  • Cigna PPO
  • Empire Blue Cross Blue Shield EPO
  • Empire Blue Cross Blue Shield HMO
  • Empire Blue Cross Blue Shield Indemnity
  • Empire Blue Cross Blue Shield MediBlue
  • Empire Blue Cross Blue Shield POS
  • Empire Blue Cross Blue Shield PPO
  • Empire Blue Cross Blue Shield Pathways, Enhanced
  • GHI CBP
  • HIP Access I
  • HIP Access II
  • HIP Child Health
  • HIP EPO/PPO
  • HIP HMO
  • HIP Medicare
  • HIP POS
  • HealthPlus Child Health (Amerigroup)
  • HealthPlus Family Health (Amerigroup)
  • HealthPlus Medicaid (Amerigroup)
  • HealthRepublic
  • HealthSmart (WTC)
  • Humana Medicare
  • Local 1199 PPO
  • MagnaCare PPO
  • Medicare
  • MultiPlan/PHCS PPO
  • NYS Empire Plan
  • Oscar
  • Oxford Exchange
  • Oxford Freedom
  • Oxford Liberty
  • Oxford Medicare
  • UPN Elite
  • United Exchange- Compass
  • UnitedHealthcare EPO
  • UnitedHealthcare HMO
  • UnitedHealthcare Medicare
  • UnitedHealthcare POS
  • UnitedHealthcare PPO
  • UnitedHealthcare Top Tier
*Insurance listed above may not be accepted at all office locations. Please confirm prior to each visit. The information presented here may not be complete or may have been changed.
NYU Cardiology Associates

530 1st Avenue, Skirball 9U
New York, NY 10016

Contact

Phone: 212-263-3967

Welcome back!

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My Research

My laboratory focuses on several facets of cardiovascular biology and disease. First, we are interested in the formation and function of the heart's specialized cardiac conduction system (CCS). This complex network comprises pacemaking cells that establish the normal rhythmicity of the heart, as well as rapidly conducting His-Purkinje cells that facilitate highly synchronized excitation of the working myocardium.

Our studies of the conduction system utilize genetically engineered mouse models that specifically visualize various components of the network. Gene profiling of microdissected CCS tissue is then employed to identify the molecular signature of these specialized cells. A complementary approach for gene discovery using murine embryonic stem cells is being developed, whereby such pluripotent cells can be differentiated into specific components of the CCS under defined cultured conditions.

A second area of investigation includes studies of arrhythmia mechanisms, focusing especially on the dysregulation of gap junction channels and the associated abnormalities in impulse propagation. These studies include a multiple of strategies that range from molecular and biochemical through genetically engineered murine models with site-specific mutations in connexin genes, which encode the gap junction channel proteins. Our laboratory was the first to demonstrate the essential role of gap junction channels in cardiac rhythmicity, using conditional knockout approaches. Current studies are focused on defining the role of post-translational regulation of connexins during normal gap junction formation and in response to pathologic stimuli that lead to abnormal gap junction remodeling.

Publications

  • Purkinje Cells as Sources of Arrhythmias in Long QT Syndrome Type 3

    Iyer, Vivek; Roman-Campos, Danilo; Sampson, Kevin J; Kang, Guoxin; Fishman, Glenn I; Kass, Robert S
    Scientific reports. 2015. 5: 13287-13287

  • Scn1b deletion leads to increased tetrodotoxin-sensitive sodium current, altered intracellular calcium homeostasis and arrhythmias in murine hearts

    Lin, Xianming; O'Malley, Heather; Chen, Chunling; Auerbach, David; Foster, Monique; Shekhar, Akshay; Zhang, Mingliang; Coetzee, William; Jalife, Jose; Fishman, Glenn I; Isom, Lori; Delmar, Mario
    Journal of physiology. 2015 Mar. 593 (6): 1389-1407

  • Genetically engineered SCN5A mutant pig hearts exhibit conduction defects and arrhythmias

    Park, David S; Cerrone, Marina; Morley, Gregory; Vasquez, Carolina; Fowler, Steven; Liu, Nian; Bernstein, Scott A; Liu, Fang-Yu; Zhang, Jie; Rogers, Christopher S; Priori, Silvia G; Chinitz, Larry A; Fishman, Glenn I
    Journal of clinical investigation. 2015 Jan. 125 (1): 403-412

Read All Publications (110)