Barry Reisberg, MD

  • Specialties: Adult Psychiatry, Geriatric Psychiatry
  • Language: English
  • Phone: 212-263-8550

About Me

Conditions and Treatments

Alzheimer's disease, memory loss, cognitive disorder, dementia, depressive disorder, bipolar disorder, memory disorders, anxiety disorder, mood disorder, psychological testing, cerebrovascular disorder
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Credentials

Positions
  • Professor, Department of Psychiatry
  • Clinical Dir Aging & Dementia Rsch Ctr
  • Director of the Zachary and Elizabeth M. Fisher Alzheimer Disease Education and Research program
Board Certifications
  • American Board of Psychiatry & Neurology - Psychiatry, 1976
Education and Training
  • Residency, Metropolitan Hospital, Psychiatry, 1975
  • MD from New York Medical College, 1972
Departments

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Locations and Appointments

Department of Psychiatry

145 East 32nd Street, Room 508
New York, NY 10016

Dept. of Psychiatry

560 First Avenue
New York, NY 10016

Research My Research

Interests

Alzheimer's disease

Research Summary

Over the past three decades I have directed research that has significantly advanced the current understanding and treatment of Alzheimer’s disease. I was the first to describe many of the most important symptoms of Alzheimer's disease, as well as its characteristic clinical course. My clinical staging measures—the Functional Assessment Staging measure and the Global Deterioration Scale—are governmentally mandated throughout the United States and in some parts of Canada and Europe, and they are recommended in Japan, Australia, and elsewhere.

My work has been instrumental in the development of all three major current pharmacological approaches to treating Alzheimer’s disease: NMDA receptor antagonist treatment (memantine); treatment for behavioral disturbances in dementia (risperidone); and cholinesterase inhibitor treatments, such as rivastigmine for mild to moderate dementia and donepezil for severe dementia.

I was the principal designer and principal investigator of the decisive trial, published in the New England Journal of Medicine, that resulted in U.S. and European Union approval of the first treatment for advanced Alzheimer’s disease, memantine.

My colleagues and I developed the concepts behind and coined the term “mild cognitive impairment,” now a clinically recognized entity. My descriptions of an even earlier stage, “subjective cognitive impairment,” are increasingly being recognized as the earliest manifestations of Alzheimer’s disease. At the other end of the severity spectrum, the staging procedures I developed have been used in pivotal worldwide trials of currently approved medications for advanced Alzheimer’s disease.

My description of the retrogenesis neurodevelopmental process in Alzheimer’s disease and related dementias is also advancing a new science of disease management and providing new insights into Alzheimer’s disease etiopathogenesis. We have recently reported that our Comprehensive, Individualized, Person-Centered Management (CI-PCM) program is 10 times more effective than either memantine or nonpharmacologic treatment alone in persons with moderately severe Alzheimer’s disease.

I have received numerous grants and awards for my research, including a Lifetime Achievement Award in Recognition of Outstanding Research from the Alzheimer’s Association and the International Conferences on Alzheimer’s Disease in 2004, the major worldwide organizations in the AD field at the time.

I am the emeritus director of the clinical core of the Alzheimer’s Disease Center, and clinical director of the Aging and Dementia Research Center. I serve as professor of psychiatry at NYU School of Medicine. I am also director of the Zachary and Elizabeth M. Fisher Alzheimer’s Disease Education and Resources Program at the NYU School of Medicine. Additionally, I am an adjunct professor at the McGill University Faculty of Medicine in Montreal, Canada.

Academic Contact

Academic office

145 East 32nd Street

Fifth Floor, Room 508

New York, NY 10016

Phone

212-263-8550

Fax

212-263-6991

Research Interests Timeline

These focus areas and their associated publications are derived from PubMed and the MeSH term library.
represents one publication
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Publications

  • Multiregional Age-Associated Reduction of Brain Neuronal Reserve Without Association With Neurofibrillary Degeneration or beta-Amyloidosis

    Wegiel, Jerzy; Flory, Michael; Kuchna, Izabela; Nowicki, Krzysztof; Yong Ma, Shuang; Wegiel, Jarek; Badmaev, Eulalia; Silverman, Wayne P; de Leon, Mony; Reisberg, Barry; Wisniewski, Thomas Wegiel, Jerzy; Flory, Michael; Kuchna, Izabela; Nowicki, Krzysztof; Yong Ma, Shuang; Wegiel, Jarek; Badmaev, Eulalia; Silverman, Wayne P; de Leon, Mony; Reisberg, Barry; Wisniewski, Thomas
    Journal of neuropathology & experimental neurology. 2017 Jun 01. 76 (6): 439-457

  • Comprehensive, Individualized, Person-Centered Management of Community-Residing Persons with Moderate-to-Severe Alzheimer Disease: A Randomized Controlled Trial

    Reisberg, Barry; Shao, Yongzhao; Golomb, James; Monteiro, Isabel; Torossian, Carol; Boksay, Istvan; Shulman, Melanie; Heller, Sloane; Zhu, Zhaoyin; Atif, Ayesha; Sidhu, Jaskirat; Vedvyas, Alok; Kenowsky, Sunnie Reisberg, Barry; Shao, Yongzhao; Golomb, James; Monteiro, Isabel; Torossian, Carol; Boksay, Istvan; Shulman, Melanie; Heller, Sloane; Zhu, Zhaoyin; Atif, Ayesha; Sidhu, Jaskirat; Vedvyas, Alok; Kenowsky, Sunnie
    Dementia geriatric & cognitive disorders. 2017 Jan 26. 43 (1-2): 100-117

  • Alzheimer's disease

    Reisberg, Barry; Franssen, Emile; Souren, Liduin EM; Kenowsky, Sunnie; Janjua, Khurram S; Veigne, Sandra W; Guillo-Benarous, Francoise; Singh, Satneet; Khizar, Asma; Shah, Umang; Shah, Romi G; Bhandal, Amandeep; Auer, Stefanie Reisberg, Barry; Franssen, Emile; Souren, Liduin EM; Kenowsky, Sunnie; Janjua, Khurram S; Veigne, Sandra W; Guillo-Benarous, Francoise; Singh, Satneet; Khizar, Asma; Shah, Umang; Shah, Romi G; Bhandal, Amandeep; Auer, Stefanie
    IN: Medical aspects of disability for the rehabilitation professionals. [New York] : Springer Publishing Company, 2017. 5th edition. p.?-?. (2558782)

Read All Publications (263)