About Me
Growing up as one of eight children, I learned the value of collaboration and teamwork. My wife and I are also very fortunate to have seven children, so I truly understand the importance of family to my patients.
Obstetrics and gynecology, and especially my focus on infertility, bring together the science and personal interactions with patients, which I love. I am incredibly invested in helping couples discover why they’ve been unable to conceive. At NYU Langone, we offer some of the most exciting fertility breakthroughs of our time, including the latest fertility drugs and genetic testing, to support couples in creating the families they want.
Before I practiced as an OB/GYN, I trained in psychiatry, which prepared me to help couples cope with the emotions that accompany reproductive choices. I empower my patients to be involved in the entire process, and I help them to weigh their options based on their unique values and goals.
Breakthroughs in contraceptive technology have given women the ability to delay having children, but by a woman’s late 30s and early 40s, the ability to conceive declines. Our research lab focuses on the causes of age-related infertility, primarily the aging of the eggs themselves. We’re working on new treatments to slow this process. We’ve also made incredible advances in in vitro fertilization, including our ability to decrease the likelihood of miscarriage by using genetic testing of the embryo to determine its integrity before transfer.
Conditions and Treatments
Conditions
- ectopic pregnancy
- endometriosis
- excessive hairiness
- fertility
- fibroids
- infertility in women
- male infertility
- menopause
- menstrual disorder
- polycystic ovary syndrome
- premature menopause
- recurrent miscarriage
Treatments
- artificial insemination
- egg donation
- egg freezing
- fertility preservation
- in vitro fertilization
- oocyte recovery
- ovulation induction
- preimplantation diagnosis
- surrogate mothers
Learn more about conditions we treat at NYU Langone:
Endometriosis , Fibroids , Infertility in Women , Male Infertility , Menopause , Polycystic Ovary Syndrome , Recurrent MiscarriageCredentials
Positions
Board Certifications
- American Board of Obstetrics & Gynecology (Reproduc Endocrin & Infertility), 1995
- American Board of Obstetrics & Gynecology - Obstetrics & Gynecology, 1993
Education and Training
- Fellowship, Yale University School of Medicine, Reproductive Endocrinology, 1992
- Fellowship, Yale University School of Medicine, Reproductive Endocrinology, 1991
- Residency, Yale New Haven Hospital, Obstetrics & Gynecology, 1989
- Fellowship, Northwestern University, Neuro-endocrinology, 1985
- Residency, University of Chicago, Psychiatry, 1985
- Residency, Cambridge Hospital, Psychiatry, 1982
- Residency, Mount Auburn Hospital, Medicine, 1981
- MD from Georgetown University, 1980
Is this your profile?
Edit profileInsurance Plans Accepted
This provider accepts the following insurance plans.
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Aetna
- Aetna HMO
- Aetna Indemnity
- Aetna International
- Aetna Medicare Advantage
- Aetna Open Access EPO
- Aetna Open Access HMO
- Aetna POS
- Aetna POS (American Express Employer)
- Aetna PPO
- Aetna Signature Administrators PPO
- Aetna Student Plan
- Allied
- Chesterfield Resources Inc
- Christian Brothers Services
- CoreSource
- Healthscope
- Nippon Life of America-Aetna
- Nippon Life-Aetna
- Starmark
- WellNet
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Blue Cross Blue Shield
- BCBS Blue Access EPO Large Group
- BCBS Blue Access EPO Small Group
- BCBS Blue Access GEPO Small Group
- BCBS Blue Access PPO Large Group
- BCBS EPO
- BCBS EPO (BlackRock Employees)
- BCBS EPO - Empire EPO (NYU Langone Employees)
- BCBS EPO - Empire EPO (Sunset Park/Family Health Center Employees)
- BCBS EPO - Empire NYU Care (NYU Langone Employees)
- BCBS EPO - Empire NYU Care (Sunset Park/Family Health Center Employees)
- BCBS Federal Program
- BCBS Florida Blue Care HMO
- BCBS Florida Blue Medicare PPO
- BCBS Florida Blue Options PPO
- BCBS Florida Blue Select
- BCBS Florida MyBlue HMO
- BCBS Florida Simply Blue
- BCBS Florida Traditional PPC
- BCBS HMO
- BCBS Indemnity
- BCBS Local 32BJ Employees
- BCBS Mediblue Medicare HMO
- BCBS Mediblue Medicare PPO
- BCBS Mediblue Select HMO/Extra HMO
- BCBS POS
- BCBS PPO
- BCBS PPO (BlackRock Employees)
- BCBS PPO (LICH Employees)
- BCBS PPO - Empire PPO (Sunset Park/Family Health Center Employees)
- BCBS PPO/EPO Small Group
- New York Hotel Trades
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Cigna
- Apwu Health Plan
- Cigna Oscar
- Cigna - Humana
- Cigna Great West PPO
- Cigna HMO
- Cigna Indemnity
- Cigna Managed Care/POS
- Cigna Medicare Advantage
- Cigna NALC
- Cigna Open Access
- Cigna Open Access PPO
- Cigna PPO
- Cigna Premier Plus
- Great West HMO
- Kaiser Permanente
- MVP-Cigna Network
- Wellfleet-NYU Student
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NYSHIP - The Empire Plan
- NYS Health Insurance Plan - The Empire Plan
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Oxford
- Oxford Health Plans Freedom
- Oxford Health Plans Liberty
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United Healthcare
- Bind Benefits inc
- UMR
- United Healthcare All Savers
- United Healthcare Choice
- United Healthcare Choice (AMEX employees)
- United Healthcare Choice (Blackrock employees)
- United Healthcare Choice (CBS employees)
- United Healthcare EPO
- United Healthcare EPO (NYU Langone Health Employees)
- United Healthcare Golden Rule Insurance
- United Healthcare HMO
- United Healthcare Indemnity
- United Healthcare Indemnity (NYU Langone Health Employees)
- United Healthcare Navigate
- United Healthcare POS
- United Healthcare PPO
- United Healthcare Plus (NYU Langone Health Employees)
- United Healthcare Student Resources
- United Healthcare Student Resources (NYU)
- United Healthcare Value, Advantage and HDHP (New York University employees)
- UnitedHealthcare Choice (NY Power Authority Employees)
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VA Community Care Network
- VA CCN Optum
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WINFertility
- WINFertility
David L. Keefe, MD does not accept insurance.
Locations and Appointments
NYU Langone Fertility Center
159 East 53rd Street, 3rd Floor, New York, NY 10022
NYU Langone Reproductive Specialists of New York
200 Old Country Road, Suite 350, Mineola, NY 11501
Research My Research
Interests
reproductive aging, oocyte dysfunction, telomeres, meiosis, stem cells, oocytes, genome integrity, stem cell biology
Research Summary
Fertility in women declines by their mid to late thirties, even while menses are regular and the rest of the body functions at near peak capacity. During this time the chance of pregnancy decreases and the chance of miscarriage increases, related to chromosome and other abnormalities in the eggs. My research group studies why a woman's eggs lose viability. We discovered changes in the chromosomes' ends, called the telomeres. We found that telomere attrition may contribute to the decreased fertility, as well as the increased miscarriage and aneuploidy risks observed in older women. We are developing tests of egg health based on measurement of telomere length. We also have shown in experimental animals that preventing telomere attrition may delay reproductive aging.Finally, we are using genomic approaches to identify the genes that influence telomere length and reproductive longevity in women.
Academic Contact
Academic office
462 First Avenue
Ninth Floor
New York, NY 10016
Phone
Research Interests Timeline
Clinical Trials and Research Studies
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Chronic Endometritis and the effect on embryo implantation: A study of women undergoing Frozen Euploid Embryo Transfer
Publications
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Berteli, Thalita S; Wang, Fang; Navarro, Paula A; Kohlrausch, Fabiana B; Keefe, David L
Journal of assisted reproduction & genetics. 2023 Aug ; 40(8):1845-1854
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Berteli, Thalita S; Wang, Fang; McKerrow, Wilson; Navarro, Paula A; Fenyo, David; Boeke, Jef D; Kohlrausch, Fabiana B; Keefe, David L
Journal of assisted reproduction and genetics. 2023 Aug ; 40(8):1835-1843
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Wiltshire, Ashley; Schaal, Renata; Wang, Fang; Tsou, Tiffany; McKerrow, Wilson; Keefe, David
Genes. 2023 Jun 08; 14(6):