Francisco J. Esteva, MD, PhD

  • Specialty: Medical Oncology
  • Languages: English, Spanish
  • Phone: 212-731-5657
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About Me

As a medical student, I was fascinated by internal medicine, a specialty that requires knowledge of multiple disciplines to reach accurate diagnoses and implement effective treatments. When I was a resident in internal medicine, I was inspired by cancer patients and the physicians and nurses who were in the trenches fighting this disease. I also became interested in the emerging field of molecular biology and its potential to revolutionize cancer therapy. I decided to become a medical oncologist to translate basic science concepts into bedside practices and improve patient outcomes.

I currently serve as the director of the breast medical oncology program at Perlmutter Cancer Center. Our program brings together surgeons, medical oncologists, radiation oncologists, pathologists, radiologists, nurses, and other specialists to improve the lives of people with breast cancer through screening, prevention, and treatment.

My main focus is on using systemic therapies, such as endocrine therapy, targeted therapy, immunotherapy, and chemotherapy, to manage breast cancer at any stage.

My patients are unique individuals, not breast cancer subjects, and I treat them this way. I learn their history and combine this information with the results of a physical examination and imaging, as well as pathology and laboratory data, to make a diagnosis and determine the best course of treatment. I empower people to make treatment decisions with me, and I support them throughout their journey.

I currently lead clinical trials evaluating the safety and effectiveness of novel treatments for women with advanced breast cancer. Our research group, consisting of experts from a diverse array of specialties, is investigating how to improve the molecular classification of breast cancer. Our goal is to identify specific subtypes of breast cancer and design the appropriate treatment for each patient.

I have received the Mentored Patient-Oriented Research Career Development Award from the National Cancer Institute and been included in the “Best Doctors in America” list. I am also a fellow of the American College of Physicians and have been inducted into the American Society for Clinical Investigation, one of the oldest medical societies in the country.


Conditions and Treatments

breast cancer

Credentials

Positions
  • Professor, Department of Medicine
  • Co Dir Phase 1 Drug Dev Pgm Div Hematology Med Onc
  • Assoc Dir of Clin Investigate Perlmutter CancerCtr
  • Dir Breast Medical Oncology Program
  • Co Dir of the Breast Cancer DMG
Education and Training
  • PhD from Zaragoza Medical School, 2001
  • Fellowship, Georgetown University Hospital, Medical Oncology, 1996
  • Residency, Cooper University Hospital, Internal Medicine, 1994
  • MD from Zaragoza Medical School, 1988
Departments

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NYU Medical Oncology Associates

160 East 34th Street, 4th Floor
New York, NY 10016

Research My Research

Interests

breast cancer

Research Summary

Dr. Esteva is interested in the clinical developoment of targeted therapies and biomarkers in breast cancer.

Research Interests Timeline

These focus areas and their associated publications are derived from PubMed and the MeSH term library.
represents one publication
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Clinical Trials

  • A randomized phase II trial of fulvestrant with or without Ribociclib after progression on aromatase inhibition plus cyclin-dependent kinase 4/6 inhibition in patients with unresectable or metastatic hormone receptor positive HER2 negative breast cancer
    Learn More
  • PALbociclib CoLlaborative Adjuvant Study: A Randomized Phase III Trial of Palbociclib With Standard Adjuvant Endocrine Therapy Versus Standard Adjuvant Endocrine Therapy Alone for Hormone Receptor Positive (HR+) / Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Early Breast Cancer
    Learn More
  • A Phase 1b Study of Safety and Immune Response to PVX-410 Vaccine Alone and in Combination with an Antibody Targeting the PD-1/PD-L1 Pathway in HLA-A2+ Subjects Who Have Completed Initial Standard Treatment of Stage II or III Triple Negative Breast Cancer
    Learn More

Publications

  • Detection and clinical implications of occult systemic micrometastatic breast cancer

    Kwa, Maryann; Esteva, Francisco J Kwa, Maryann; Esteva, Francisco J
    IN: The breast : comprehensive management of benign and malignant diseases. Philadelphia, PA : Elsevier, [2018]. 5th ed. p.858-866. (2745292)

  • DUSP4 is associated with increased resistance against anti-HER2 therapy in breast cancer

    Menyhart, Otilia; Budczies, Jan; Munkacsy, Gyongyi; Esteva, Francisco J; Szabo, Andras; Miquel, Teresa Puig; Gyorffy, Balazs Menyhart, Otilia; Budczies, Jan; Munkacsy, Gyongyi; Esteva, Francisco J; Szabo, Andras; Miquel, Teresa Puig; Gyorffy, Balazs
    Oncotarget. 2017 Sep 29. 8 (44): 77207-77218

  • Duration of response and tumor shrinkage with first-line ribociclib plus letrozole in postmenopausal women with HR1, HER2-ABC [Meeting Abstract]

    Janni, W; Alba Conejo, E; Bachelot, T; Diab, S; Gil-Gil, M; Beck, TJ; Ryvo, L; Lopez, R; Tsai, M; Esteva, FJ; Zamora Aunon, MP; Kral, Z; Ward, P; Richards, P; Pluard, TJ; Sutradhar, S; Miller, M; Campone, M Janni, W; Alba Conejo, E; Bachelot, T; Diab, S; Gil-Gil, M; Beck, TJ; Ryvo, L; Lopez, R; Tsai, M; Esteva, FJ; Zamora Aunon, MP; Kral, Z; Ward, P; Richards, P; Pluard, TJ; Sutradhar, S; Miller, M; Campone, M
    Annals of oncology. 2017 SEP. 28: ?-?

Read All Publications (161)