For as long as I can remember, I have wanted to be a doctor. When I was a medical student, I helped care for a young pregnant woman who had severe heart failure. I realized then that I wanted to help women who struggle to become pregnant, and to safely deliver babies of women who have high-risk pregnancies. The experience led me to the fields of obstetrics and gynecology and maternal fetal medicine. My goal is to ensure the safety of both patients—mother and child.
My work in prenatal care reduces the risks pregnant women may face from conditions such as diabetes, hypertension, and thyroid issues. I performed one of the country’s first intrauterine fetal transfusions for rhesus hemolytic disease, or Rh disease, in which the blood of a fetus and mother are incompatible, at NYU Langone. I was also the first doctor in the world to repair a ruptured fetal membrane. In 1975, I established the NYU Langone maternal fetal medicine division, of which I served as the director until 2005. Currently I am the director of NYU Langone’s Pregnancy Loss Prevention Center.
I have published 122 peer-reviewed articles on subjects including fetal heart rate patterns, the fetal immune system, and risk assessment for high-risk pregnancies. Additionally, I have co-authored two books for the general reader, Miscarriage, Medicine & Miracles and The Intellectual Devotional: Health. I have been recognized as one of New York Magazine’s “Best Doctors in New York” and “Top Minimally Invasive Surgeons.”
I believe in a personal approach to medicine, and I am completely committed to providing the care, treatment, and support that each of my patients requires. I try to teach this caring approach to the students, residents, and fellows whom I have been privileged to help train as doctors.
Conditions and Treatments
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- Silverman Professor of Obstetrics and Gynecology, Department of Obstetrics and Gynecology
- American Board of Obstetrics & Gynecology (Maternal-Fetal Medicine), 1975
- American Board of Obstetrics & Gynecology - Obstetrics & Gynecology, 1970
Education and Training
- Fellowship, NYU Medical Center, Reproductive Endo., 1968
- Residency, Bellevue Hospital Center, OB-GYN, 1968
- Residency, NYU Medical Center, OB/GYN, 1968
- MD from New York University, 1963
Locations and Appointments
Research My Research
luteal phase defects, pregnancy loss, fetal physiology, endoscopic surgery, immunology, stem cells, amniotic fluid, drug toxicity, aneuploidy
Fetal blood of different gestational ages was tested for immunoreactivity and compared with maternal blood responses to immune stimulators. The data will help with transplatation of stem cells, autoimmune disease,asthma, and preterm birth Mid-trimester amniotic fluid was cultured in various media, frozen, thawed with retention of stem cell function and induced to neural and osteocyte fates. Studies are underway to determine the potential role of amniotic fluid stem cells in correcting defects and damage. Factors controlling longevity and cell death in amniotic fluid cultures are being studied by Affymetrix gene analysis and quantitative PCR for genes related to senesence. Studies on effects of drugs on fetal development in amniotic cell cultures have shown potential for in vitro perinatal drug testing. Clinical effectiveness of prevention of pregnancy loss by the Pregnancy Loss Prevention Center is being studied.
530 First Avenue
Fifth Floor, 5G
New York, NY 10016
Research Interests Timeline
Stem cells & development. 2016 10 ; 25(20):1570-1579
American journal of obstetrics & gynecology. 2016 Mar ; 214(3):321-7
Journal of regenerative medicine. 2014; 3:1