About Me
I’ve always been fascinated by how our brains allow us to think, move, and experience the world, and how these seemingly universal abilities can be significantly impacted by brain disorders. My interests led me to receive training in both clinical skills and basic experimental sciences of movement disorders.
As a physician–scientist at NYU Langone, I provide care for people who have Parkinson’s disease and related movement disorders, including tremor, tics, dystonia, and Huntington’s disease, using the best available treatments.
I’m the director of translational research at the Fresco Institute for Parkinson’s and Movement Disorders at NYU Langone, where I strive to learn more about how disease affects patients in their daily lives on an individual level. I apply my knowledge and clinical bedside experience to my research to further discover the underlying mechanisms of disease. These insights help me understand what patients experience, so I can provide them with the best possible approach to care.
Before joining NYU Langone, I created and led a multidisciplinary team of basic researchers and clinical experts at the University of Chicago for two decades. More recently, I was the chief of the division of movement disorders in the Department of Neurology at Columbia University.
Conditions and Treatments
Conditions
- progressive supranuclear palsy
- spasmodic dysphonia
- Parkinson's disease
- essential tremor
- tic disorder
- dystonia
- Lewy body dementia
- ataxia
- multiple system atrophy
- chorea
Learn more about conditions we treat at NYU Langone:
Movement Disorders in Adults, Parkinson’s Disease, Dementia, Autonomic DisordersCredentials
Positions
- Founders Professor of Neurology, Department of Neurology at NYU Grossman School of Medicine
- Professor, Department of Neuroscience and Physiology at NYU Grossman School of Medicine
- Director, Translational Research, Department of Neurology
Board Certifications
- American Board of Psychiatry & Neurology - Neurology, 1987
Education and Training
- Fellowship, NY Presbyterian - Columbia University Medical Center, Movement Disorders, 1987
- Residency, NY Presbyterian - Columbia University Medical Center, Neurology, 1986
- MD from Johns Hopkins University, 1982
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Aetna
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Locations and Appointments
Video Visits
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Schedule a Video VisitNYU Movement Disorders
222 East 41st Street
New York, NY 10017
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You can schedule appointments, view test results, communicate with your doctor, and more using our portal, MyChart at NYU Langone Health.Research My Research
Interests
Parkinson's disease, movement disorders, basal ganglia circuit, neural plasticity, catecholamine, biomarkers
Research Summary
My research is a part of multidisciplinary effort by a team of basic and clinical scientists to understand the mechanisms underlying Parkinson’s disease (PD) and related movement disorders. I pioneered experimental gene therapy approaches to replace dopamine for PD. My laboratory research now focuses on understanding how brain circuitry is perturbed by the dopamine loss and by pharmacological treatment in mouse models of PD. We hope to understand the mechanisms of exercise, rehabilitation, medication, and surgical intervention in PD. We are also exploring circuitry mechanisms underlying gait and freezing and non-motor symptoms of PD that have not been adequately addressed by the current therapies.
In addition, we are interested in the molecular dysfunctions that contribute to neuronal degeneration in PD and translating this knowledge into PD-specific biomarkers that can help us to predict, diagnose, and understand heterogeneity of Parkinson’s disease better. These tools may allow us to improve our individualized care of patients and facilitate the development of new therapies.
Academic Contact
Academic office
435 E 30th Street, Science Building
13th floor, 1305
New York, NY 10016
Lab Website
Clinical Trials and Research Studies
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Synucleinopathy and Constipation: A Prospective Observational Study of the Physiology of Constipation in Comparison to Chronic Idiopathic Constipation
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THE MOUNT SINAI MOVEMENT DISORDER STUDY
Publications
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Choi, Se Joon; Ma, Thong C; Ding, Yunmin; Cheung, Timothy; Joshi, Neal; Sulzer, David; Mosharov, Eugene V; Kang, Un Jung
eLife. 2020 07 20; 9:
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Kang, Un Jung; Boehme, Amelia K; Fairfoul, Graham; Shahnawaz, Mohammad; Ma, Thong Chi; Hutten, Samantha J; Green, Alison; Soto, Claudio
Movement disorders. 2019 Apr ; 34(4):536-544
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Zhuang, Xiaoxi; Mazzoni, Pietro; Kang, Un Jung
Nature reviews. Neurology. 2013 May ; 9(5):248-56