Welcome to the

Pearl I. Barlow Center for Memory Evaluation & Treatment

We provide the treatment and support you need when dealing with memory loss.

At NYU Langone’s Pearl I. Barlow Center for Memory Evaluation and Treatment, we provide early diagnosis and the appropriate treatments for memory loss, coupled with the support services needed to strengthen you and your family for the journey ahead.

Regarded as one of New York City’s most comprehensive clinical treatment centers for memory disorders of all origins, the Pearl I. Barlow Center for Memory Evaluation and Treatment is dedicated to helping patients manage memory disorders. We offer:

  • a team approach to care delivered by experienced neurologists, psychologists, social workers, and nurse practitioners
  • caring, knowledgeable, and empathetic staff who work together to support the patient, caregiver, and family
  • clinicians who are involved in active research projects to better understand the genetics and progression of Alzheimer’s disease and develop new treatments 

As part of NYU Langone’s Center for Cognitive Neurology and Silberstein Alzheimer’s Institute, our focus is on addressing the needs of those experiencing Alzheimer’s disease, mild cognitive impairment, frontotemporal degeneration, progressive aphasias, and other dementias as a result of neurodegenerative disease. For individuals diagnosed with Lewy body dementia, we have a specialty clinic dedicated to testing and treatment. 

We also offer programs in cognitive remediation for older adults with concerns about their memory, as well as those with mild cognitive impairment. 

We understand that these conditions affect you in numerous ways, changing the way you think, function, feel, and act. By using the most advanced treatments, technologies, and research options available, we provide you with diagnostic testing, assessments for the cause of your memory loss, MRI scanning and evaluation, neurological evaluations, tailored treatment plans, psychotherapy, compassionate care, and cognitive remediation. 

We know your diagnosis affects your family members and caregivers as well, so we offer them appropriate support, resources, and services. Our clinical social workers provide individual, couples, and group psychotherapy for patients and their families.

Your First Visit

There is no single test to diagnose dementia. At our center, the diagnosis is made by a global assessment of the patient’s history, a clinical exam, and pencil-and-paper tests. A few of the steps we take include:

  • a consultation with an experienced neurologist who is an expert in dementia diagnosis and treatment
  • a detailed review of the patient’s medical history, including past and present brain scans
  • a neurological examination assessing higher cortical function, such as memory, language, attention, visuospatial function, and judgment
  • diagnostic testing, including blood tests and brain MRI, as well as single-photon emission computerized tomography (SPECT) or PET scanning, if needed
  • development of a treatment plan that may include medications to slow memory loss, non-pharmacological approaches, psychotherapy, or cognitive therapy
  • counseling to discuss questions and to review your doctor’s recommendations

For your first visit, we recommend that you bring a loved one or caregiver with you who can help answer questions about your memory changes and take notes. We also ask you to bring your medical history and copies of any prior brain scans and neurological examinations assessing your memory, language, attention, visuospatial function, and judgment skills. 

Patients are given the opportunity to enroll in clinical trials at NYU Langone’s Alzheimer’s Disease Research Center, as well as to participate in imaging and biomarker studies that are part of NYU Langone’s Center for Brain Health. In addition, the Pearl I. Barlow Center for Memory Evaluation and Treatment works closely with the Center for Cognitive Neurology’s clinical trial programs. Recommendations for a wide array of available clinical trials are tailored to individual patients. 

About Pearl I. Barlow

The Pearl I. Barlow Center for Memory Evaluation and Treatment was created through the generosity of the late Pearl Ida Barlow. After caring for her aging parents, she wanted to contribute to a center that would give comprehensive care to the elderly and aging.


More About Our Memory Programs

Our Team

Our physicians include experts in neurology and psychiatry who focus on aging and dementia treatments.

View All Doctors

Our Leadership

  • Thomas M. Wisniewski, MD
    Clinical Director | Neurology

    In addition to being the clinical director of the Pearl I. Barlow Center for Memory Evaluation and Treatment, Dr. Wisniewski is director of NYU Langone’s Center of Cognitive Neurology and director of the Conformational Disorders Laboratory. For more than 20 years, Dr. Wisniewski’s research team has been working on understanding Alzheimer's disease and prion diseases, as well as other disorders such as Down's syndrome and autism, with the aim of developing new treatment strategies. This work has led Dr. Wisniewski to publish more than 240 peer-reviewed articles. His work has been continuously funded by the National Institutes of Health for more than 20 years.

    View Full Profile

Plan Your Visit

Our Location

Pearl I. Barlow Center for Memory Evaluation & Treatment

145 East 32nd Street
2nd Floor
New York, NY 10016