Kathleen A. Haines, MD

  • Specialty: Pediatrics
  • Languages: English, Spanish
  • Phone: 201-996-5306

Credentials

Positions
  • Adjunct Associate Professor, Department of Medicine
  • Adjunct Associate Professor, Department of Pediatrics
Board Certifications
  • American Board of Allergy & Immunology - Allergy & Immunology, 1981
  • American Board of Allergy & Immunology (Clinical & Laboratory Immunology), 1981
  • American Board of Pediatrics - Pediatrics, 1980
Education and Training
  • Fellowship, NYU Medical Center, Rheumatology, 1982
  • Fellowship, New York Presbyterian - Weill Cornell Medical Center, Allergy & Immunology, 1980
  • Residency, New York Presbyterian - Weill Cornell Medical Center, Pediatrics, 1977
  • MD from Albert Einstein College Of Med, 1975
Departments

Locations and Appointments

16 Insurance Plans Accepted
  • Aetna EPO
  • Cigna EPO
  • Cigna HMO
  • Cigna Indemnity
  • Cigna POS
  • Empire BCBS Child Health Plus
  • Empire BCBS EPO
  • Empire BCBS HMO
  • Empire BCBS Healthy NY
  • Empire BCBS Indemnity
  • Empire BCBS POS
  • Empire BCBS PPO
  • Multiplan
  • Oxford Freedom Plan
  • Oxford Medicare
  • Private Healthcare Systems (PHCS)
*Insurance listed above may not be accepted at all office locations. Please confirm prior to each visit. The information presented here may not be complete or may have been changed.

Hackensack University Med Ctr, 30 Prospect Avenue
Hackensack, NJ 07601

Contact

Phone: 201-996-5306

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My Research

A critical host defense mechanism in response to bacterial infection or tissue injury is an influx of polymorphonuclear neutrophilic leukocytes, or neutrophils, to the affected area. Once at the inflamed site, the neutrophils ingest, or phagocytose, bacteria or damaged tissue and release toxic oxygen metabolites (O2H2O2) and proteolytic enzymes to digest the phagocytosed material. Activation of these neutrophils is initiated by local production of compounds known as chemoattractants, either by the body or the invading bacteria. Similarly, bacteria that have been "tagged" by antibodies binding to their surface also provoke activation of neutrophils. However, in autoimmune diseases in which the body "tags" its own tissue with antibodies, this response becomes pathologic as the neutrophils trigger inappropriate inflammation.

We study the intracellular signals produced by neutrophils after activation by chemoattractants, aggregated immune complexes, and antibody-coated particles. We have used a unique protein produced by Neisseria gonorrhoea (Por) as a probe to dissect which signals are requried for the idscrete responses of chemotaxis, O2 generation, and lysosomal enzyme release. Pretreatment of neutrophils with Por inhibits the release of granule enzymes triggered by chemoattractants and, in parallel, inhibits the production of the diglyceride class of second messengers. Interestingly, Por does not inhibit neutrophil function triggered by immune complexes thus indicating that chemoattractants and immune complexes activate different signaling pahtways. We continue to examine the relationship of other signals such as protein kinases, phosphatases, and lipid products to neutrophil function in bacterial infection and pathologic inflammation to help us understand and control this important aspect of both health and disease.

Publications

  • Vitamin D deficiency is common and associated with increased C-reactive protein in children and young adults with lupus: an Atherosclerosis Prevention in Pediatric Lupus Erythematosus substudy

    Robinson, Angela Byun; Tangpricha, Vin; Yow, Eric; Gurion, Reut; McComsey, Grace A; Schanberg, Laura E; Ardoin, Stacy; Dewitt, Esi Morgan; Rabinovich, C Egla; Ellis, Janet; Mieszkalski, Kelly; Wootton, Janet; Chira, Peter; Hsu, Joyce; Lee, Tzielan; Sandborg, Christy; Perea, Jan; Gottlieb, Beth; Irigoyen, Patricia; Luftig, Jennifer; Siddiqi, Shaz; Ni, Zhen; Orlando, Marilynn; Pagano, Eileen; Eichenfield, Andrew; Imundo, Lisa; Levy, Deborah; Kahn, Philip; Batres, Candido; Cabral, Digna; Haines, Kathleen A; Kimura, Yukiko; Li, Suzanne C; Weiss, Jennifer; Riordan, Mary Ellen; Vaidya, Beena; von Scheven, Emily; Mietus-Snyder, Michelle; Silverman, Earl; Ng, Lawrence; Bowyer, Suzanne; Ballinger, Susan; Klausmeier, Thomas; Hinchman, Debra; Hudgins, Andrea; Punaro, Marilynn; Henry, Shirley; Zhang, Shuzen; Singer, Nora G; Brooks, Elizabeth B; Miner, Stacy; Szabo, Nancy; Scalzi, Lisabeth; Sherry, David; Dorfeld, Libby; Wilson, Sarajane; Tress, Jenna; McCurdy, Deborah; Hernandez, Tatiana; Vitale, Jyotsna; Klein-Gitelman, Marisa; Kress, Angela; Lowe, Nicole; Patel, Falguni; Wallace, Carol; Hamilton, Stephanie; Silver, Richard; Caldwell, Katie; Kamen, Diane; Wagner-Weiner, Linda; Puplava, Becky; Lonchev, Atanas; Higgins, Gloria; Bacani, Monica; Brunner, Hermine; Rutherford, Cynthia; Meyers-Eaton, Jamie; Nelson, Shannen; Grom, Alexei; Jung, Larry; Conway, Teresa; Frank, Lacey; Kuss, Lori; Soep, Jenny; Senz, Hazel; Reed, Ann; Mason, Thomas; Jaquith, Jane; Paepke-Tollefsrud, Diana E
    Lupus science & medicine. 2014. 1 (1): e000011-e000011 e000011

  • Vitamin D status is a determinant of atorvastatin effect on carotid intima medial thickening progression rate in children with lupus: an Atherosclerosis Prevention in Pediatric Lupus Erythematosus (APPLE) substudy

    Robinson, Angela Byun; Tangpricha, Vin; Yow, Eric; Gurion, Reut; Schanberg, Laura E; McComsey, Grace A; Ardoin, Stacy; Dewitt, Esi Morgan; Rabinovich, C Egla; Ellis, Janet; Mieszkalski, Kelly; Wootton, Janet; Chira, Peter; Hsu, Joyce; Lee, Tzielan; Sandborg, Christy; Perea, Jan; Gottlieb, Beth; Irigoyen, Patricia; Luftig, Jennifer; Siddiqi, Shaz; Ni, Zhen; Orlando, Marilynn; Pagano, Eileen; Eichenfield, Andrew; Imundo, Lisa; Levy, Deborah; Kahn, Philip; Batres, Candido; Cabral, Digna; Haines, Kathleen A; Kimura, Yukiko; Li, Suzanne C; Weiss, Jennifer; Riordan, Mary Ellen; Vaidya, Beena; von Scheven, Emily; Mietus-Snyder, Michelle; Silverman, Earl; Ng, Lawrence; Bowyer, Suzanne; Ballinger, Susan; Klausmeier, Thomas; Hinchman, Debra; Hudgins, Andrea; Punaro, Marilynn; Henry, Shirley; Zhang, Shuzen; Singer, Nora G; Brooks, Elizabeth B; Miner, Stacy; Szabo, Nancy; Scalzi, Lisabeth; Sherry, David; Dorfeld, Libby; Wilson, Sarajane; Tress, Jenna; McCurdy, Deborah; Hernandez, Tatiana; Vitale, Jyotsna; Klein-Gitelman, Marisa; Kress, Angela; Lowe, Nicole; Patel, Falguni; Wallace, Carol; Hamilton, Stephanie; Silver, Richard; Caldwell, Katie; Kamen, Diane; Wagner-Weiner, Linda; Puplava, Becky; Lonchev, Atanas; Higgins, Gloria; Bacani, Monica; Brunner, Hermine; Rutherford, Cynthia; Meyers-Eaton, Jamie; Nelson, Shannen; Grom, Alexei; Jung, Larry; Conway, Teresa; Frank, Lacey; Kuss, Lori; Soep, Jenny; Senz, Hazel; Reed, Ann; Mason, Thomas; Jaquith, Jane; Paepke-Tollefsrud, Diana E
    Lupus science & medicine. 2014. 1 (1): e000037-e000037 e000037

  • A22: consensus treatment plans for induction therapy in childhood proliferative lupus nephritis-status of use in daily clinical care

    von Scheven, Emily; Punaro, Marilynn; Ardoin, Stacy P; Brunner, Hermine; Hsu, Joyce J; Mehta, Jay; Wagner-Weiner, Linda; Klein-Gitelman, Marisa; Rouster Stevens, Kelly; Haines, Kathleen A; Schanberg, Laura; Eberhard, B Anne
    Arthritis & rheumatology. 2014 Mar. 66 Suppl 11: S35-S36

Read All Publications (77)