David R. Wise, MD, PhD

  • Specialty: Medical Oncology
  • Language: English
  • Phone: 212-731-6366
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About Me

I first encountered cancer when I was eight years old and a close family member was diagnosed with the disease. During this frightening and uncertain time, my family and I relied on the medical oncologist for guidance and support. I was drawn to a career in medical oncology because I wanted to provide people with this same care and compassion.

In addition to pursuing a medical degree, I obtained a PhD in cancer biology because I wanted to thoroughly understand cancer from all angles. My extensive training enables me to keep up with the rapidly evolving science of oncology, and that, in turn, allows me to provide my patients with the most innovative cancer therapies.

At Perlmutter Cancer Center, I specialize in working with people who have prostate cancer. I am my patients’ best advocate—listening to their goals and needs and encouraging them along the way. The journey that I start with my patients is personal and powerful, and together, we navigate a way forward.

In my research, I aim to develop new diagnostics and therapeutics to better individualize prostate cancer treatment. I also seek to identify novel therapies that can reactivate the immune systems of people who have prostate cancer.


Conditions and Treatments

metastatic prostate cancer, prostate cancer, recurrent prostate cancer

Credentials

Positions
  • Assistant Professor, Department of Medicine
  • Assistant Professor, Department of Urology
Education and Training
  • Residency, New York Presbyterian-Weill Cornell Medical Center, Internal Medicine, 2013
  • MD from University Of Pennsylvania, 2011
  • PhD from University Of Pennsylvania, 2011
  • Fellowship, Memorial Sloan Kettering Cancer Center, Medical Oncology,
Departments

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NYU Medical Oncology Associates

160 East 34th Street, 10th Floor
New York, NY 10016

NYU Urology Associates

135 East 31st Street, 2nd Floor
New York, NY 10016

Research Research Interests Timeline

These focus areas and their associated publications are derived from PubMed and the MeSH term library.
represents one publication
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Clinical Trials

  • A phase Ib open-label dose escalation and expansion study to investigate the safety pharmacokinetics pharmacodynamics and clinical activity of GSK525762 in combination with androgen deprivation therapy and other agents in subjects with castrate-resistant prostate cancer (CRPC)
    Learn More
  • TRITON2: A Multicenter Open-label Phase 2 Study of Rucaparib in Patients with Metastatic Castration-resistant Prostate Cancer Associated with Homologous Recombination Deficiency
    Learn More
  • TRITON3: A Multicenter Randomized Open-label Phase 3 Study of Rucaparib versus Physician s Choice of Therapy for Patients with Metastatic Castration-resistant Prostate Cancer Associated with Homologous Recombination Deficiency
    Learn More

Publications

  • Androgen Receptor Pathway-Independent Prostate Cancer Is Sustained through FGF Signaling

    Bluemn, Eric G; Coleman, Ilsa M; Lucas, Jared M; Coleman, Roger T; Hernandez-Lopez, Susana; Tharakan, Robin; Bianchi-Frias, Daniella; Dumpit, Ruth F; Kaipainen, Arja; Corella, Alexandra N; Yang, Yu Chi; Nyquist, Michael D; Mostaghel, Elahe; Hsieh, Andrew C; Zhang, Xiaotun; Corey, Eva; Brown, Lisha G; Bluemn, Eric G; Coleman, Ilsa M; Lucas, Jared M; Coleman, Roger T; Hernandez-Lopez, Susana; Tharakan, Robin; Bianchi-Frias, Daniella; Dumpit, Ruth F; Kaipainen, Arja; Corella, Alexandra N; Yang, Yu Chi; Nyquist, Michael D; Mostaghel, Elahe; Hsieh, Andrew C; Zhang, Xiaotun; Corey, Eva; Brown, Lisha G; Nguyen, Holly M; Pienta, Kenneth; Ittmann, Michael; Schweizer, Michael; True, Lawrence D; Wise, David; Rennie, Paul S; Vessella, Robert L; Morrissey, Colm; Nelson, Peter S
    Cancer cell. 2017 Oct 09. 32 (4): 474-489.e6
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  • Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

    Wise, David R; DeBerardinis, Ralph J; Mancuso, Anthony; Sayed, Nabil; Zhang, Xiao-Yong; Pfeiffer, Harla K; Nissim, Ilana; Daikhin, Evgueni; Yudkoff, Marc; McMahon, Steven B; Thompson, Craig B Wise, David R; DeBerardinis, Ralph J; Mancuso, Anthony; Sayed, Nabil; Zhang, Xiao-Yong; Pfeiffer, Harla K; Nissim, Ilana; Daikhin, Evgueni; Yudkoff, Marc; McMahon, Steven B; Thompson, Craig B
    Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2008 Dec 02. 105 (48): 18782-18787

  • Glutamine addiction: a new therapeutic target in cancer

    Wise, David R; Thompson, Craig B Wise, David R; Thompson, Craig B
    Trends in biochemical sciences. 2010 Aug. 35 (8): 427-433

Read All Publications (11)