Matthias Karajannis at [NYU Langone Medical Center]

Matthias A. Karajannis, MD

  • Specialties: Pediatric Oncology, Pediatric Hematology, Pediatrics
  • Languages: English, French, German
  • Phone: 212-263-8400

About Me

Conditions and Treatments

brain tumor, spinal cord tumor, brain cancer, neurofibromatosis, glioma, astrocytoma, medulloblastoma, primitive neuroectodermal tumor (PNET), acoustic neuroma, meningioma, pineal tumor, malignant schwannoma, pituitary tumor, choroid plexus papilloma, childhood cancer
Show More Conditions
Learn more about conditions we treat at NYU Langone:
Childhood Brain & Spinal Cord Tumors, Spinal Cord Tumors, Neurofibromatosis, Childhood Sarcomas



  • Associate Professor, Department of Pediatrics
  • Associate Professor, Department of Otolaryngology

Board Certifications

  • AB Pediatrics - Pediatrics

Education and Training

  • 2006
  • Fellowship, Memorial Sloan-Kettering Cancer Center, Pediatric Neuro-Oncology
  • 2005
  • Fellowship, Memorial Sloan-Ketteriing Cancer Center, Pediatrics(Hemo/Onc)
  • 2002
  • Residency, Duke University Medical Center, Pediatrics
  • 1992
  • MD from Free University - Berlin


Locations and Appointments

63 Insurance Plans Accepted
  • Aetna Indemnity
  • Aetna Medicare
  • Aetna POS
  • Aetna PPO/EPO
  • Affinity
  • Affinity Exchange- Essential
  • Cigna EPO/POS
  • Cigna PPO
  • ElderPlan
  • Empire Blue Cross Blue Shield EPO
  • Empire Blue Cross Blue Shield HMO
  • Empire Blue Cross Blue Shield Healthy NY
  • Empire Blue Cross Blue Shield Indemnity
  • Empire Blue Cross Blue Shield MediBlue
  • Empire Blue Cross Blue Shield POS
  • Empire Blue Cross Blue Shield PPO
  • Empire Blue Cross Blue Shield Pathways, Enhanced
  • Fidelis Child Health
  • Fidelis Exchange
  • Fidelis Family Health
  • Fidelis Medicaid
  • Fidelis Medicare
  • HIP Access I
  • HIP Access II
  • HIP Child Health
  • HIP Family Health
  • HIP Medicaid
  • HIP Medicare
  • HealthPlus Child Health (Amerigroup)
  • HealthPlus Family Health (Amerigroup)
  • HealthPlus Medicaid (Amerigroup)
  • HealthRepublic
  • HealthSmart (WTC)
  • Humana Medicare
  • Local 1199 PPO
  • MagnaCare PPO
  • Medicare
  • MetroPlus Child Health
  • MetroPlus Exchange Plans
  • MetroPlus Family Health
  • MetroPlus Medicaid
  • MultiPlan/PHCS PPO
  • NY Medicaid
  • NYS Empire Plan
  • Oscar
  • Oxford Exchange
  • Oxford Freedom
  • Oxford Liberty
  • Oxford Medicare
  • UPN Elite
  • United Exchange- Compass
  • UnitedHealthcare Community & State Plan
  • UnitedHealthcare EPO
  • UnitedHealthcare HMO
  • UnitedHealthcare Medicare
  • UnitedHealthcare POS
  • UnitedHealthcare PPO
  • UnitedHealthcare Top Tier
  • Visiting Nurse Service (VNS) Medicare
*Insurance listed above may not be accepted at all office locations. Please confirm prior to each visit. The information presented here may not be complete or may have been changed.

Stephen D. Hassenfeld Childrens Center for Cancer & Blood Disorders
160 East 32nd Street, 3rd Floor
New York, NY 10016


Phone: 212-263-8400

Welcome back!

As a returning patient for this doctor, please schedule an appointment using your MyChart at NYU Langone account.

Learn more about MyChart at NYU Langone.

My Research

As a pediatric neuro-oncologist with a special interest in translational research and developing novel, molecular targeted therapies, my work focuses on nervous system tumors, including those arising in the setting of tumor disposition syndromes, such as neurofibromatosis. I am an NIH-funded investigator and currently serve as PI on several single and multi-institutional clinical-translational trials, as well as investigator of the Department of Defense/CDMRP NF Clinical Trials Consortium. In a number of translational laboratory projects related to NF and brain tumors, I collaborate with other scientists from NYU and other institutions. Specific areas of investigation include the ErbB receptor family, RAS-RAF-MEK-ERK and mTOR signaling pathways. On a national level, I am involved in clinical protocol development with molecular targeted agents for children with brain tumors as a member of the Childrens's Oncology Group CNS Committee.


  • Neurofibromatosis-related tumors: emerging biology and therapies

    Karajannis, Matthias A; Ferner, Rosalie E 2015 Feb; 26-33, Current opinion in pediatrics — id: 1459772, year: 2015, page: 26, stat: Journal Article
  • Clinical response to bevacizumab in schwannomatosis

    Blakeley, Jaishri; Schreck, Karisa C; Evans, D Gareth; Korf, Bruce R; Zagzag, David; Karajannis, Matthias A; Bergner, Amanda L; Belzberg, Allan J 2014 Nov; 1986-1987, Neurology — id: 1368962, year: 2014, page: 1986, stat: Journal Article
  • Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations

    Buczkowicz, Pawel; Hoeman, Christine; Rakopoulos, Patricia; Pajovic, Sanja; Letourneau, Louis; Dzamba, Misko; Morrison, Andrew; Lewis, Peter; Bouffet, Eric; Bartels, Ute; Zuccaro, Jennifer; Agnihotri, Sameer; Ryall, Scott; Barszczyk, Mark; Chornenkyy, Yevgen; Bourgey, Mathieu; Bourque, Guillaume; Montpetit, Alexandre; Cordero, Francisco; Castelo-Branco, Pedro; Mangerel, Joshua; Tabori, Uri; Ho, King Ching; Huang, Annie; Taylor, Kathryn R; Mackay, Alan; Bendel, Anne E; Nazarian, Javad; Fangusaro, Jason R; Karajannis, Matthias A; Zagzag, David; Foreman, Nicholas K; Donson, Andrew; Hegert, Julia V; Smith, Amy; Chan, Jennifer; Lafay-Cousin, Lucy; Dunn, Sandra; Hukin, Juliette; Dunham, Chris; Scheinemann, Katrin; Michaud, Jean; Zelcer, Shayna; Ramsay, David; Cain, Jason; Brennan, Cameron; Souweidane, Mark M; Jones, Chris; Allis, C David; Brudno, Michael; Becher, Oren; Hawkins, Cynthia 2014 May; 451-456, Nature genetics — id: 970142, year: 2014, page: 451, stat: Journal Article
Read All Publications (55)