David Rapoport at [NYU Langone Medical Center]

David M. Rapoport, MD

  • Specialty: Pulmonary Medicine
  • Language: English
  • Phone: 212-263-8423

About Me

Conditions and Treatments

snoring, breathing disorder during sleeping, sleep disorder, dyssomnia, restless leg syndrome (RLS), chronic respiratory failure, hypoventilation

Credentials

Positions
  • Adjunct Professor, Department of Medicine
Board Certifications
  • American Board of Family Medicine (Sleep Medicine), 2007
  • American Board of Internal Medicine (Pulmonary Disease), 1980
  • American Board of Internal Medicine - Internal Medicine, 1977
Education and Training
  • Fellowship, NYU Medical Center, Pulmonary Disease, 1979
  • Residency, St. Luke's Roosevelt Hospital, Internal Medicine, 1977
  • MD from Albert Einstein College Of Med, 1974
Departments

Locations and Appointments

View Insurance Plans Accepted
  • Aetna
    • Aetna HMO
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    • Aetna POS
    • Aetna PPO/EPO
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    • Affinity
    • Affinity Exchange- Essential
  • Cigna
    • Cigna EPO/POS
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    • Emblem Select Care Exchange
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    • Empire Blue Cross Blue Shield EPO
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    • HIP Access I
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    • HealthSmart (WTC)
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    • Humana Medicare
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    • Local 1199 PPO
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    • NY Medicaid
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NYU Langone Sleep Disorders Center

462 1st Avenue, Suite 7N3
New York, NY 10016

Contact

Phone: 212-263-8423

Welcome back!

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Research My Research


The recently described clinical syndrome of obstructive sleep apnea (OSAS), possibly affecting 2% to 10% of the adult population, is characterized by episodic sleep-induced changes in upper airway patency. These produce respiratory compromise ranging from partial to complete occlusion. Because obstruction represents a major challenge to homeostatic respiratory control mechanisms and because it can be completely reversed with a simple nasal mask/airway pressure device known as a nasal CPAP, OSAS provides an extraordinary opportunity to study control of breathing in humans.



Upper airway obstruction in OSAS results from interaction between subtle anatomic airway narrowing, increased wall collapsibility due sleep-induced loss of baseline muscle tone, and insufficient inspiratory phasic dilator muscle contraction to oppose the negative intraluminal pressure resulting from diaphragmatic contraction. This collapsible behavior can be modelled with a Starling resistor; exploring the properties of this model should provide insights into pathophysiology and treatment. One key observation is that a sinusoidally varying driving force (inspiratory diaphragmatic drive) acting through such a collapsible tube results in an inspiratory waveform which "flow limits." Although defined by pressure/flow relationships, flow limitation can be recognized by a flat contour of the inspiratory waveform in the flow/time display.



Appreciation of the information content of this easily obtained and noninvasive measurement has provided three research directions in our laboratory: 1) defining the role of the upper airway in sleep-related changes in respiratory control in normal subjects and patients with cardiorespiratory failure resulting in apnea and chronic hypercapnia; 2) developing diagnostic techniques to screen patients for the occurrence of sleep-related respiratory abnormalities; and 3) developing a technique for closed-loop computer-controlled regulation of the treatment for OSAS, e.g., a variation on nasal CPAP which automatically seeks the optimal pressure on a continuous basis.



Publications

  • Physiological and psychological factors influencing continuous positive airway pressure (CPAP) use in world trade center (WTC) responders with Obstructive Sleep Apnea (OSA) [Meeting Abstract]

    Ducca, E L; Twumasi, A; Gumb, T; Perez, A; Lewis, C P; Patel, R; Alimokhtari, S; Black, K; Chitkara, N; Sunderram, J; Rapoport, D M; Ayappa, I Ducca, E L; Twumasi, A; Gumb, T; Perez, A; Lewis, C P; Patel, R; Alimokhtari, S; Black, K; Chitkara, N; Sunderram, J; Rapoport, D M; Ayappa, I
    Sleep. 2016 2016. 39: A158-A158

  • Pattern of CPAP use differs in mild and positional OSA: Preliminary results from the WTC SNORE Study [Meeting Abstract]

    Gupta, S; Ducca, E L; Gumb, T; Twumasi, A; Perez, A; Black, K; Lu, S; Rapoport, D M; Ayappa, I; Alimokhtari, S; Sunderram, J Gupta, S; Ducca, E L; Gumb, T; Twumasi, A; Perez, A; Black, K; Lu, S; Rapoport, D M; Ayappa, I; Alimokhtari, S; Sunderram, J
    Sleep. 2016 2016. 39: A152-A152

  • Unique medical issues in adult patients with mucopolysaccharidoses

    Mitchell, John; Berger, Kenneth I; Borgo, Andrea; Braunlin, Elizabeth A; Burton, Barbara K; Ghotme, Kemel A; Kircher, Susanne G; Molter, David; Orchard, Paul J; Palmer, James; Pastores, Gregory M; Rapoport, David M; Wang, Raymond Y; White, Klane Mitchell, John; Berger, Kenneth I; Borgo, Andrea; Braunlin, Elizabeth A; Burton, Barbara K; Ghotme, Kemel A; Kircher, Susanne G; Molter, David; Orchard, Paul J; Palmer, James; Pastores, Gregory M; Rapoport, David M; Wang, Raymond Y; White, Klane
    European journal of internal medicine. 2016 Jun 11. 34: 2-10

Read All Publications (191)