Cervical Cancer Radiation Therapy

Doctors at NYU Langone may use radiation therapy—high levels of energy directed at cancer cells—instead of surgery to treat small tumors confined to the cervix. Radiation therapy may also be used after surgery to kill any remaining cancer cells or before surgery to shrink tumors.

Our doctors often combine radiation therapy and chemotherapy—the use of drugs to kill cancer cells throughout the body—for larger tumors that are confined to the cervix or for cancer that has spread to other areas of the body. Chemotherapy may also make tumor cells more sensitive to radiation therapy.

Treatment Planning and Guidance

If you receive a diagnosis of cervical cancer, our radiation oncologists may use CT, MRI, and PET scans of the cervix and surrounding tissue and organs, in conjunction with computer planning software, to tailor a treatment plan for you.

This software creates a three-dimensional image of the tumor and surrounding organs and allows our doctors to determine how best to target the cervical cancer while sparing healthy tissue, especially the bladder, which stores and empties urine, and the rectum, the last portion of the digestive tract.

This image-guided radiation therapy shows the precise location of your organs, which can move slightly as you breathe or move during treatment. The technique also allows doctors to track the size and shape of the tumor over several weeks, as radiation therapy begins to shrink the cancer.

Targeted radiation therapy may also help to minimize the amount of radiation that reaches the ovaries, helping to preserve fertility.

Types of Radiation Therapy

NYU Langone doctors use external beam radiation therapy, stereotactic body radiation therapy, or brachytherapy to manage cervical cancer.

External Beam Radiation Therapy

External beam radiation therapy is delivered from outside the body to the tumor using a machine called a linear accelerator. This machine rotates around you during therapy, delivering radiation to the tumor from different directions, while minimizing the radiation exposure in nearby healthy tissue.

At NYU Langone, our radiation oncologists use a variety of technologies to deliver highly targeted radiation therapy, tailored to the size, shape, and location of the tumor. For example, they often use an approach called intensity modulated radiation therapy, which allows them to break up the radiation beams into many smaller doses of different strengths, or “minibeams,” so they can precisely treat the cancer.

Some forms of external beam radiation therapy require that the linear accelerator start and stop for treatment adjustments. But at NYU Langone, doctors can offer a technology called volumetric modulated arc therapy, in which the machine moves around you in one or several nonstop, 360-degree rotations. This approach lets doctors adjust the angle and intensity of the radiation beams as they are delivered. And because this therapy proceeds without interruption, treatment sessions may be shorter than with other approaches.

Usually, external beam radiation therapy is given once a day, five days a week, for several weeks.

Stereotactic Body Radiation Therapy

Stereotactic body radiation therapy delivers a few high doses of carefully targeted radiation beams to the tumor over several days. Your doctor may use this approach for small cervical cancer tumors or for those that return after other treatments. As with other forms of radiation therapy at NYU Langone, this approach uses imaging guidance to target the tumor while avoiding healthy tissue.

High-Dose-Rate Brachytherapy

In brachytherapy, doctors temporarily place radioactive beads or pellets inside the body to treat cervical cancer. Often, this internal radiation is combined with external beam radiation therapy to manage cervical tumors.   

With high-dose-rate brachytherapy to manage cervical cancer, doctors at NYU Langone place the beads inside your body using either an intracavitary or an interstitial approach.

During intracavitary brachytherapy for women who no longer have a uterus, the doctor places an applicator with radioactive material into the vagina for several minutes, after which it is removed. In women who have a uterus, the radiation is placed in the upper vagina and in the uterus. Doctors may use a local anesthetic to ensure your comfort during the procedure.

If the cancer has spread to an area of the pelvis not easily accessed with the intracavitary approach, the doctor may use the interstitial approach. This involves placing the radiation directly in or near the tumor using a needle or catheter, which is a thin hollow tube. This procedure requires either general anesthesia or regional anesthesia, in which an anesthetic is inserted into the spine with a hollow needle and catheter and numbs the pelvic area.

Our doctors may use brachytherapy for several minutes at a time over the course of a few days or weeks on an outpatient or inpatient basis.

Managing Side Effects

NYU Langone doctors carefully plan your radiation therapy to minimize side effects such as fatigue, nausea, and irritation to the bladder and rectum, which may cause diarrhea or blood in the urine or stool. Our range of supportive and integrative services can also help you to manage radiation side effects.

Although our radiation oncologists use highly targeted treatments to help avoid triggering early menopause, which is when a woman stops having her menstrual period at a younger age than expected, this is still possible. Our gynecologic oncologists and fertility experts can discuss options for preserving your ability to have children.

More Cervical Cancer Resources